涎腺肿瘤中的肌上皮细胞标志物
1传统的MEC标志物,2新兴的MEC标志物,3展望,4参考文献
[摘要]涎腺肿瘤中具有肌上皮分化的占大部分,而肌上皮细胞及其变异型在常规切片中难以辨认,常需要免疫组织化学给予鉴别。因此,肌上皮细胞的免疫组织化学标志物成为研究的热点。本文就近几年来涎腺肿瘤肌上皮细胞的免疫组织化学标志物研究进展作一综述。[关键词]肌上皮细胞;标志物;涎腺肿瘤
[中图分类号]R 73[文献标志码]A[doi]10.3969/j.issn.1673-5749.2012.01.020
The myoepithelial cell markers in salivary gland tumorsZhu Xiaojie, Zhang Jiali, Chen Xinming.[The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)& Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China]
[Abstract]There are a large part of salivary gland tumors with myoepithelial cell(MEC)differentiation. Owing to the confusion in identifying the MEC and its variants, immunohistochemical staining was often used to make differential diagnosis. Therefore, biomarkers for MEC have drawn considerable attention recently. This review will summarize the development of the myoepithelial markers in salivary gland tumors.
[Key words]myoepithelial cell;marker;salivary gland tumor
涎腺肿瘤是口腔颌面部的常见肿瘤,其中具有肌上皮细胞(myoepithelial cell,MEC)分化能力的较多,如良性肿瘤中的多形性腺瘤、肌上皮瘤、基底细胞腺瘤 ......
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