[摘要]腭裂是颌面部较常见的先天性发育畸形，其原发或继发畸形均会影响患者的口颌系统功能和身心健康。牵张成骨(DO)是矫治颌面部骨骼畸形和组织缺损的新型外科技术之一，利用其矫治先天性腭裂的原发或继发畸形的研究已取得一定的效果。本文对动物实验和临床应用中的术期选择、手术、牵张装置的设计、牵张时机、可能的并发症及其预后等方面进行综述，以诠释DO技术在关闭原发性腭裂裂隙、延长硬腭长度、矫治牙槽突裂、矫治继发性上颌骨发育不全中的研究和应用。

    [关键词]腭裂；骨缺损；牵张成骨术

    [中图分类号]R 782.2+2[文献标志码]A[doi]10.3969/j.issn.1673-5749.2012.01.0**

    Research progress on distraction osteogenesis in treatment of cleft palate deformitiesYu Ruixue1, Wang Dawei1, Chen Yiyang2.(1. Dept. of Orthodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun YatSen University, Guangzhou 510055, China; 2. Dept. of Stomatology, Guangzhou Children’s Hospital, Guangzhou 510120, China)

    [Abstract]Cleft palate is one of the most common congenital deformities, which may do harm to the function of stomatological system and psychological health. Repairing bone defect of cleft palate has been focused by researchers. Distraction osteogenesis(DO)is one of the new techniques of repairing maxillofacial deformity. Using DO to repair bone defect of cleft palate is proved to be effective. This article introduced the device of distraction, timing, design of the operation, complications and prognosis. We also reviewed the investigation and application of DO on hard palate closure and lengthening, alveolar cleft closure and maxillary retrusion correcting. ......