牡蛎散合生脉饮对气阴两虚型甲亢患者的临床疗效及肝功能的影响(1)

http://www.100md.com 2017年4月1日 《世界中医药》 20177

     摘要 目的：分析牡蠣散合生脉饮对气阴两虚型甲亢患者的临床疗效及肝功能的影响。方法：选取2015年1月至2016年12月在张家港市中医医院确诊治疗的气阴两虚型甲亢患者50例，以数字随机表法均分到2组，每组25例。对照组服用丙基硫氧嘧啶片治疗，治疗组服用牡蛎散合生脉饮治疗，2组均治疗2个月。观察2组患者临床疗效、血清FT3、FT4、TSH水平变化及肝功能指标(ALT、AST、γ-GT、TBIL)变化，并对2组患者中医证候进行积分比较。结果：治疗组总有效率(92.00%)略大于对照组(80.00%)，2组比较差异无统计学意义( P >0.05)。2组患者经治疗后患者的FT3、FT4、ALT、AST、γ-GT、TBIL水平均降低，而TSH水平均升高，差异有统计学意义( P <0.05)；治疗组治疗后FT3、FT4、ALT、AST均低于对照组，差异有统计学意义( P <0.05)。治疗组治疗后中医证候积分为(1.28±0.65)分，略低于对照组，2组中医证候积分比较，差异无统计学意义( P >0.05)。结论：牡蛎散合生脉饮能够有效治疗气阴两虚型甲亢患者，对患者的甲状腺素水平及肝功能的异常均有显著改善作用。
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    关键词 牡蛎散合生脉饮；气阴两虚型甲亢；肝功能

    Effect of Muli Powder Combined with Shanghai Decoction on Patients of Dual Deficiency of Qi and Yin Type of Hyperthyroidism and Liver Function

    Yuan Jie， Li Hong， Cui Yan

    (Endocrinology Department of Zhangjiagang City Hospital of Traditional Chinese Medicine， Zhangjiagang 215600， China)

    Abstract Objective： To analyze the clinical effect of Muli powder and Shengmai decoction on patients with dual deficiency of Qi and Yin type of hyperthyroidism as well as liver function. Methods： A total of 60 cases diagnosed of dual deficiency of Qi and Yin type of hyperthyroidism admitted into our hospital from January 2015 to December 2016 in our hospital were selected， then randomly divided into two groups， with 25 cases in each. The control group was given Hyperthyroidism Ling capsule and the observation group was given Muli powder and Shengmai decoction for 2 months. The clinical efficacy， serum FT3， FT4， TSH levels and liver function indexes (ALT， AST，-GT， TBIL) of the two groups were observed and compared. Results： The total effective rate of the observation group (92.00%) was slightly greater than that of the control group (80.00%)， and there was no significant difference between the two groups ( P >0.05). After treatment， FT3， FT4， ALT， AST，-GT， TBIL gamma level of the two groups decreased， while the level of TSH increased， the difference was statistically significant ( P <0.05). FT3， FT4， ALT， AST in observation group after treatment were lower than those of the control group， and the difference was statistically significant ( P <0.05). After treatment， TCM syndrome score of the treatment group was (1.28±0.65) points， slightly lower than that of the control group， without statistical difference ( P >0.05). Conclusion： Muli powder and Shengmai Decoction can effectively treat patients with dual deficiency of Qi and Yin type of hyperthyroidism. It can also improve thyroid hormone levels and liver function of patients., 百拇医药(袁婕 李红 崔艳)

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