中药抗肿瘤作用的物质基础与网络机制研究(8)
[39]Kim SJ，Kim AK.Antibreast cancer activity of fine black ginseng(Panax ginseng Meyer.)and ginsenoside Rg5[J].J Ginseng Res，2015，39(2)：125134.
[40]Zhang Z，Du GJ，Wang CZ，et al.Compound K，a Ginsenoside Metabolite，Inhibits Colon Cancer Growth via Multiple Pathways Including p53p21 Interactions[J].Int J Mol Sci，2013，14(2)：29802995.
[41]Wang W，Rayburn ER，Hao M，et al.Experimental therapy of prostate cancer with novel natural product anticancer ginsenosides[J].Prostate，2008，68(8)：809819.
, 百拇医药
[42]Cheng CC，Yang SM，Huang CY，et al.Molecular mechanisms of ginsenoside Rh2mediated G1 growth arrest and apoptosis in human lung adenocarcinoma A549 cells[J].Cancer Chemother Pharmacol，2005，55(6)：531540.
[43]Kim JS，bJoo EJ，Chun J，et al.Induction of apoptosis by ginsenoside Rk1 in SKMEL2human melanoma[J].Arch Pharm Res，2012，35(4)：717722.
[44]Zuo G，Guan T，Chen D，et al.Total saponins of Panax ginseng induces K562 cell differentiation by promoting internalization of the erythropoietin receptor[J].Am J Chin Med，2009，37(4)：747757.
, http://www.100md.com
[45]Fujimoto J，Sakaguchi H，Aoki I，et al.Inhibitory effect of ginsenosideRb2 on invasiveness of uterine endometrial cancer cells to the basement membrane[J].European Journal of Gynaecological Oncology，2001，22(5)：339341.
[46]Li L，Wang Y，Qi B，et al.Suppression of PMAinduced tumor cell invasion and migration by ginsenoside Rg1 via the inhibition of NFκBdependent MMP9 expression[J].Oncol Rep，2014，32(5)：17791786.
[47]Lee SG，Kang YJ，Nam JO.AntiMetastasis Effects of Ginsenoside Rg3 in B16F10 Cells[J].J Microbiol Biotechnol，2015，25(12)：19972006.
, http://www.100md.com
[48]Guo JQ，Zheng QH，Chen H，et al.Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE adherin/EphA2/MMP9/MMP2 expression[J].International Journal of Oncology，2014，45(3)：1065.
[49]Jung JS，Ahn JH，Le TK，et al.Protopanaxatriol ginsenoside Rh1 inhibits the expression of matrix metalloproteinases and the in vitro invasion/migration of human astroglioma cells[J].Neurochem Int，2013，63(2)：8086.
, 百拇医药
[50]Kim SY，Kim DH，Han SJ，et al.Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells[J].Biochem Pharmacol，2007，74(11)：16421651.
[51]Yoon JH，Choi YJ，Cha SW，et al.Antimetastatic effects of ginsenoside Rd via inactivation of MAPK signaling and induction of focal adhesion formation[J].Phytomedicine，2012，19(3/4)：284292.
[52]Kim H，Roh HS，Kim JE，et al.Compound K attenuates stromal cellderived growth factor 1(SDF1)induced migration of C6 glioma cells[J].Nutr Res Pract，2016，10(3)：259264., http://www.100md.com(张宝月 郑一夫 庞晓丛)
[40]Zhang Z，Du GJ，Wang CZ，et al.Compound K，a Ginsenoside Metabolite，Inhibits Colon Cancer Growth via Multiple Pathways Including p53p21 Interactions[J].Int J Mol Sci，2013，14(2)：29802995.
[41]Wang W，Rayburn ER，Hao M，et al.Experimental therapy of prostate cancer with novel natural product anticancer ginsenosides[J].Prostate，2008，68(8)：809819.
, 百拇医药
[42]Cheng CC，Yang SM，Huang CY，et al.Molecular mechanisms of ginsenoside Rh2mediated G1 growth arrest and apoptosis in human lung adenocarcinoma A549 cells[J].Cancer Chemother Pharmacol，2005，55(6)：531540.
[43]Kim JS，bJoo EJ，Chun J，et al.Induction of apoptosis by ginsenoside Rk1 in SKMEL2human melanoma[J].Arch Pharm Res，2012，35(4)：717722.
[44]Zuo G，Guan T，Chen D，et al.Total saponins of Panax ginseng induces K562 cell differentiation by promoting internalization of the erythropoietin receptor[J].Am J Chin Med，2009，37(4)：747757.
, http://www.100md.com
[45]Fujimoto J，Sakaguchi H，Aoki I，et al.Inhibitory effect of ginsenosideRb2 on invasiveness of uterine endometrial cancer cells to the basement membrane[J].European Journal of Gynaecological Oncology，2001，22(5)：339341.
[46]Li L，Wang Y，Qi B，et al.Suppression of PMAinduced tumor cell invasion and migration by ginsenoside Rg1 via the inhibition of NFκBdependent MMP9 expression[J].Oncol Rep，2014，32(5)：17791786.
[47]Lee SG，Kang YJ，Nam JO.AntiMetastasis Effects of Ginsenoside Rg3 in B16F10 Cells[J].J Microbiol Biotechnol，2015，25(12)：19972006.
, http://www.100md.com
[48]Guo JQ，Zheng QH，Chen H，et al.Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE adherin/EphA2/MMP9/MMP2 expression[J].International Journal of Oncology，2014，45(3)：1065.
[49]Jung JS，Ahn JH，Le TK，et al.Protopanaxatriol ginsenoside Rh1 inhibits the expression of matrix metalloproteinases and the in vitro invasion/migration of human astroglioma cells[J].Neurochem Int，2013，63(2)：8086.
, 百拇医药
[50]Kim SY，Kim DH，Han SJ，et al.Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells[J].Biochem Pharmacol，2007，74(11)：16421651.
[51]Yoon JH，Choi YJ，Cha SW，et al.Antimetastatic effects of ginsenoside Rd via inactivation of MAPK signaling and induction of focal adhesion formation[J].Phytomedicine，2012，19(3/4)：284292.
[52]Kim H，Roh HS，Kim JE，et al.Compound K attenuates stromal cellderived growth factor 1(SDF1)induced migration of C6 glioma cells[J].Nutr Res Pract，2016，10(3)：259264., http://www.100md.com(张宝月 郑一夫 庞晓丛)