中药抗肿瘤作用的物质基础与网络机制研究(9)
[53]Huynh DL，Sharma N，Kumar SA，et al.Antitumor activity of wogonin，an extract from Scutellaria baicalensis，through regulating different signaling pathways[J].Chinese Journal of Natural Medicines，2017，15(1)：1540.
[54]Chen YC，Shen SC，Lee WR，et al.Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SKHEP1[J].Archives of Toxicology，2002，76(56)：351359.
, 百拇医药
[55]Wang J，Yu Y，Hashimoto F，et al.Baicalein induces apoptosis through ROSmediated mitochondrial dysfunction pathway in HL60 cells[J].International Journal of Molecular Medicine，2004，14(4)：62732.
[56]Chang WH，Chen CH，Lu FJ.Different effects of baicalein，baicalin and wogonin on mitochondrial function，glutathione content and cell cycle progression in human hepatoma cell lines[J].Planta Medica，2002，68(2)：128132.
[57]Murashima T，Katayama H，Shojiro K，et al.Possible mechanism of growth inhibition by Scutellaria baicalensis in an estrogenresponsive mouse tumor cell line[J].Oncology Reports，2011，25(5)：14311438.
, 百拇医药
[58]Park KI，Park HS，Kang SR，et al.Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrixmetalloproteinase2 activity in human lung cancer cells[J].J Ethnopharmacol，2011，133(2)：634641.
[59]Huang ST，Wang CY，Yang RC，et al.Wogonin，an active compound in Scutellaria baicalensis，induces apoptosis and reduces telomerase activity in the HL60 leukemia cells[J].Phytomedicine International Journal of Phytotherapy & Phytopharmacology，2010，17(1)：4754.
, 百拇医药
[60]Zhang DY，Wu J，Ye F，et al.Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis[J].Cancer Research，2003，63(14)：40374043.
[61]Lu Z，Lu N，Li C，et al.Oroxylin A inhibits matrix metalloproteinase2/9 expression and activation by upregulating tissue inhibitor of metalloproteinase2 and suppressing the ERK1/2 signaling pathway[J].Toxicology Letters，2012，209(3)：211220.
[62]Honda H，Nagai Y，Matsunaga T，et al.Glycyrrhizin and isoliquiritigenin suppress the LPS sensor tolllike receptor 4/MD2 complex signaling in a different manner[J].J Leukoc Biol，2012，91(6)：967976.
, 百拇医药
[63]Yu J，Lou Y.Influence of αglycyrrhizic Acid on Metabolism of Steroid Hormone in Kidney[J].Chinese Journal of Traditional Medical Science and Technology，2006，13(4)：246247.
[64]Nakamura S，Watanabe T，Tanigawa T，et al.Isoliquiritigenin Ameliorates IndomethacinInduced Small Intestinal Damage by Inhibiting NODLike Receptor Family，Pyrin DomainContaining 3 Inflammasome Activation[J].Pharmacology，2018，101(56)：236245., 百拇医药(张宝月 郑一夫 庞晓丛)
[54]Chen YC，Shen SC，Lee WR，et al.Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SKHEP1[J].Archives of Toxicology，2002，76(56)：351359.
, 百拇医药
[55]Wang J，Yu Y，Hashimoto F，et al.Baicalein induces apoptosis through ROSmediated mitochondrial dysfunction pathway in HL60 cells[J].International Journal of Molecular Medicine，2004，14(4)：62732.
[56]Chang WH，Chen CH，Lu FJ.Different effects of baicalein，baicalin and wogonin on mitochondrial function，glutathione content and cell cycle progression in human hepatoma cell lines[J].Planta Medica，2002，68(2)：128132.
[57]Murashima T，Katayama H，Shojiro K，et al.Possible mechanism of growth inhibition by Scutellaria baicalensis in an estrogenresponsive mouse tumor cell line[J].Oncology Reports，2011，25(5)：14311438.
, 百拇医药
[58]Park KI，Park HS，Kang SR，et al.Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrixmetalloproteinase2 activity in human lung cancer cells[J].J Ethnopharmacol，2011，133(2)：634641.
[59]Huang ST，Wang CY，Yang RC，et al.Wogonin，an active compound in Scutellaria baicalensis，induces apoptosis and reduces telomerase activity in the HL60 leukemia cells[J].Phytomedicine International Journal of Phytotherapy & Phytopharmacology，2010，17(1)：4754.
, 百拇医药
[60]Zhang DY，Wu J，Ye F，et al.Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis[J].Cancer Research，2003，63(14)：40374043.
[61]Lu Z，Lu N，Li C，et al.Oroxylin A inhibits matrix metalloproteinase2/9 expression and activation by upregulating tissue inhibitor of metalloproteinase2 and suppressing the ERK1/2 signaling pathway[J].Toxicology Letters，2012，209(3)：211220.
[62]Honda H，Nagai Y，Matsunaga T，et al.Glycyrrhizin and isoliquiritigenin suppress the LPS sensor tolllike receptor 4/MD2 complex signaling in a different manner[J].J Leukoc Biol，2012，91(6)：967976.
, 百拇医药
[63]Yu J，Lou Y.Influence of αglycyrrhizic Acid on Metabolism of Steroid Hormone in Kidney[J].Chinese Journal of Traditional Medical Science and Technology，2006，13(4)：246247.
[64]Nakamura S，Watanabe T，Tanigawa T，et al.Isoliquiritigenin Ameliorates IndomethacinInduced Small Intestinal Damage by Inhibiting NODLike Receptor Family，Pyrin DomainContaining 3 Inflammasome Activation[J].Pharmacology，2018，101(56)：236245., 百拇医药(张宝月 郑一夫 庞晓丛)