便通胶囊预防急性心肌梗死PTCA术后便秘的临床观察(1)
摘要 目的：觀察便通胶囊预防急性心肌梗死经皮冠状动脉腔内血管成形术(PTCA)术后便秘及心血管事件的临床疗效。方法：选取2015年10月至2016年10月北京安贞医院收治的急性心肌梗死患者80例，按照随机数字表法分为对照组和观察组，每组40例。对照组患者给予芪蓉润肠口服液治疗，观察组给予便通胶囊治疗，2组均连续治疗4周后，观察患者便秘发生率、便秘症状评分、首次排便时间、住院时间、最大心肌耗氧增加量、心血管事件和不良反应。结果：观察组患者术后便秘发生率、便秘症状评分低于对照组，差异有统计学意义(P<0.05)；观察组术后首次排便时间和住院时间短于对照组，差异有统计学意义(P<0.05)；观察组最大心肌耗氧量显著少于对照组，差异有统计学意义(P<0.05)；2组心血管事件与药物不良反应发生率差异无统计学意义(P>0.05)。结论：便通胶囊对急性心肌梗死PTCA术后便秘有预防作用，从而降低排便时最大心肌耗氧量，有减少心血管事件发生的趋势，安全性良好。
关键词 便秘；急性心肌梗死；PTCA术；便通胶囊
, 百拇医药
Abstract Objective：To explore the clinical efficacy of Biantong Capsule in prevention of constipation and cardiovascular reaction of patients with acute myocardial infarction after percutaneous transluminal coronary angioplasty (PTCA).Methods：A total of 80 patients with acute myocardial infarction treated in Beijing Anzhen Hospital of Capital Medical University were selected and divided into control group and observation group according to the random number table method，with 40 cases in each group.The control group was given Qirong Runchang oral liquid while the observation group was given Biantong capsule for 4 week.The incidence of constipation，the constipation symptom scores，the postoperative defecation time for the first time，the length of hospital stay，the biggest addition of myocardial oxygen consumption and the adverse reactions were observed and compared.Results：The incidence of constipation and constipation symptom scores in the observation group were lower than that of the control group，and it was statistically significant (P<0.05).And the first time of postoperative defecation and hospitalization time in the observation group were lower than the control group，and the difference was statistically significant (P<0.05).The maximum myocardial oxygen consumption of the observation group was significantly lower than that of the control group，and the difference was statistically significant (P<0.05).There was no significant difference in the incidence of cardiovascular events and adverse drug reactions between the 2 groups (P>0.05).Conclusion：Biantong Capsule has effective clinical efficacy on patients with constipation after PTCA in acute myocardial infarction.It can reduce the maximum myocardial oxygen consumption during defecation and the incidence of cardiovascular events，which is safe and worthy of expanding the sample size for further observation.
Key Words Constipation； Acute myocardial infarction； Percutaneous transluminal coronary angioplasty (PTCA)； Biantong Capsule, 百拇医药(邹以席 李全)
关键词 便秘；急性心肌梗死；PTCA术；便通胶囊
, 百拇医药
Abstract Objective：To explore the clinical efficacy of Biantong Capsule in prevention of constipation and cardiovascular reaction of patients with acute myocardial infarction after percutaneous transluminal coronary angioplasty (PTCA).Methods：A total of 80 patients with acute myocardial infarction treated in Beijing Anzhen Hospital of Capital Medical University were selected and divided into control group and observation group according to the random number table method，with 40 cases in each group.The control group was given Qirong Runchang oral liquid while the observation group was given Biantong capsule for 4 week.The incidence of constipation，the constipation symptom scores，the postoperative defecation time for the first time，the length of hospital stay，the biggest addition of myocardial oxygen consumption and the adverse reactions were observed and compared.Results：The incidence of constipation and constipation symptom scores in the observation group were lower than that of the control group，and it was statistically significant (P<0.05).And the first time of postoperative defecation and hospitalization time in the observation group were lower than the control group，and the difference was statistically significant (P<0.05).The maximum myocardial oxygen consumption of the observation group was significantly lower than that of the control group，and the difference was statistically significant (P<0.05).There was no significant difference in the incidence of cardiovascular events and adverse drug reactions between the 2 groups (P>0.05).Conclusion：Biantong Capsule has effective clinical efficacy on patients with constipation after PTCA in acute myocardial infarction.It can reduce the maximum myocardial oxygen consumption during defecation and the incidence of cardiovascular events，which is safe and worthy of expanding the sample size for further observation.
Key Words Constipation； Acute myocardial infarction； Percutaneous transluminal coronary angioplasty (PTCA)； Biantong Capsule, 百拇医药(邹以席 李全)
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