摘要 目的：探讨肾炎四味片对慢性肾小球肾炎(CGN)的临床疗效及对免疫功能和炎性反应指标的影响。方法：选取2015年2月至2017年5月三峡大学附属仁和医院收治的CGN患者116例，按照随机数字表法随机分为观察组和对照组，每组58例，2组均给予控制血压、限制饮食等常规治疗，对照组给予贝那普利口服，观察组给予肾炎四味片治疗。比较2组临床疗效、治疗前后血清炎性因子水平、24 h尿蛋白定量(24 h pro)及免疫功能变化。结果：治疗后观察组总有效率为93.10%，显著高于对照组的79.31%(P<0.05或P<0.01)，且观察组显著低于对照组(P<0.05或P<0.01)，CD8+比例明显降低(P<0.01)，与对照组比较，差异均有统计学意义(均P

    关键词 慢性肾小球肾炎；肾炎四味片；疗效；炎性因子；免疫功能

    Abstract Objective：To study the clinical efficacy of Nephritis Siwei Tablet on chronic glomerulonephritis (CGN) and its influence on immune function and inflammation indexes.Methods：A total of 116 CGN cases in Affiliated Renhe Hospital of China Three Gorges University from February 2015 to May 2017 were selected and randomly divided into observation group and control group with 58 cases in each group.The 2 groups were given conventional treatment such as controlling blood pressure ......