摘要 综合中医药文献多数学者认为痰瘀毒三邪致病使动脉硬化闭塞症(ASO)在治疗上颇为棘手。本文初步对痰瘀毒在ASO中病因病机的理论基础进行归纳，并结合临床典型验案探讨运用解毒化痰、祛瘀通脉法治疗血脉瘀阻、热毒内蕴型ASO发病的作用机制。为进一步研究解毒化痰祛瘀煎剂干预ASO脂质代谢、血液流变、多种炎性反应因子等因素在发挥何种作用，从而为深化中医痰瘀毒理论打下基础。为缩短ASO治愈时间，提高疗效，减少截肢率，寻求中西医结合治疗该病的佳径。

    关键词 痰瘀毒;动脉硬化闭塞症;理论

    Abstract Most scholars in literatures of traditional Chinese medicine(TCM)think that the pathogenesis of phlegm， blood stasis and toxin makes the treatment of arteriosclerosis occlusion(ASO)rather difficult.This paper summarizes the theoretical basis of etiology and pathogenesis of phlegm ......