张林 薛小琴 胡樱丽

    摘要 膜性肾病(Membranous Nephropathy，MN)是一种慢性肾脏疾病，发病高峰期在30～50岁，60%～80%膜性肾病表现为肾病综合征。特发性膜性肾病(Idiopathic Membranous Nephropathy，IMN)，约占膜性肾病的2/3，根据尿蛋白的量可以分成低危、中危、高危3个等级。中医学认为，“大气”亏虚是高危IMN的发病原因，进而导致“大气”“滞而不运、脱而不升、散而不聚”的病理状态，临床根究“大气”的不同病理状态，可以从“补气清源、活血澄源、固肾复源”3方面来治疗高危IMN，对临床有一定指导意义。

    关键词 高危;特发性膜性肾病;大气;蛋白尿;感染;血栓栓塞

    Abstract Membranous Nephropathy(MN) is a kind of chronic nephritic disease.The peak period of onset is from 30 to 50 years old，and 60% to 80% of membranous nephropathy is characterized by nephrotic syndrome(NS).Idiopathic Membranous Nephropathy(IMN) accounts for about 2/3 of membranous nephropathy.According to the amount of urine protein，it can be divided into three grades：the low，medium and high-risk.TCM holds that “Da Qi” deficiency is the etiology of high-risk IMN，leading “Da Qi” to the pathology of “delay shipment，and do not rise，but not to get together”.Clinical research on the different pathological states of “Da Qi” shows that high-risk IMN from three aspects of “tonifying qi and clearing the source，promoting blood circulation and clarifying the source ......