单味中药有效成分抗心血管病变的分子机制
纤维化,线粒体,氧化应激
陈聪 夏君彦 李冬 林谦摘要 单味中药治疗心血管疾病分子机制涉及抗氧化应激、抗纤维化、抑制细胞凋亡、抗炎症和改善线粒体功能等方面,现对单味中药在心血管疾病中的作用进行综述,旨在为心血管病的防治提供参考。
关键词 中药有效成分;分子机制;心血管病变;氧化应激;纤维化;细胞凋亡;炎症;线粒体
Molecular Mechanism of the Effective Ingredients of Single Chinese Medicinal Against Cardiovascular Diseases
CHEN Cong1, XIA Junyan2, LI Dong2, LIN Qian1
(1 Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China; 2 Dongfang Hospital,
Beijing University of Chinese Medicine, Beijing 100078, China)
Abstract The molecular mechanism of single Chinese medicinal in the treatment of cardiovascular disease involves anti-oxidative stress, anti-fibrosis, inhibition of cell apoptosis, anti-inflammatory and improvement of mitochondrial function etc. This paper reviews the role of single Chinese medicinal in cardiovascular disease, in order to provide reference for the prevention and treatment of cardiovascular disease. ......
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