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脑梗死急性期C反应蛋白水平对患者预后的预测价值
http://www.100md.com 2012年1月9日 中国医药导报 2011年第33期
     蔡政云

    [摘要] 目的:研究脑梗死急性期C反应蛋白(CRP)水平对脑梗死预后的预测价值。方法:收集我院急性脑梗死患者217例,分为C反应蛋白正常组(CRP≤3 mg/L,115例)和C反应蛋白增高组(CRP>3 mg/L,102例),对患者随访1年,计算危险比(risk ratio,RR)以比较预后。结果:脑梗死患者CRP增高组预后明显较差。3、6、12个月后的RR死亡分别为3.76、2.58和2.08(均P<0.05),而3、6、12个月的RR再发脑梗分别为4.51、3.38和2.93(均P<0.05)。结论:脑梗死急性期C反应蛋白水平检测能有效评估患者的预后。

    [关键词] C反应蛋白;脑梗死;预后

    [中图分类号] R743.3[文献标识码] B[文章编号]1673-7210(2011)11(c)-098-02

    The prognostic significance of C-reactive protein level in patients with acute cerebral infarction

    CAI Zhengyun

    The Fourth People's Hospital of Changde City, Hu'nan Province, Changde 415000, China

    [Abstract] Objective: To study the prognostic significance of C-reactive protein (CRP) level in patients with acute cerebral infarction. Methods: 217 patients with acute cerebral infarction were selected, and the patients were divided into CRP normal group (CRP≤3 mg/L, 115 cases) and CRP increase group (CRP>3 mg/L, 102 cases). A follow-up of 1 year was finished. The risk ratio (RR) was calculated to assess the correlations between the concentration of CRP and prognosis. Results: CRP increase group had significantly worse prognosis. RRDeath after 3 months, 6 months and 12 months were 3.76, 2.58 and 2.08 (all P<0.05), and RRRecurrent cerebral infarction were 4.51, 3.38 and 2.93 respectively (all P<0.05). Conclusion: CRP level of the acute cerebral infarction has a sufficient value as a predictor of the prognosis in patients with cerebral infarction. ......

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