陈彩霞 韩瑞兰 苏秀兰

    [摘要] 尽管近几十年来化疗药物在治疗癌症方面取得了很大的进展，但当前化疗药物存在的问题仍然很多，如存在的毒性、特异性较低以及易产生耐药性，探讨新型疗法成为当前的研究热点。生物活性肽是一类对生物机体的生命活动有特殊生理功能的肽类化合物，是由二至多个氨基酸组成的二肽或多肽。它们的生物学功能多样，如免疫调节、抗高血压、抗癌、抗菌、抗炎以及其他作用，其抗癌活性尤为突出，且在很大程度上优于传统的化疗药物，所以成为当今世界范围关注的热点，从而为抗癌新型疗法的研究奠定基础。

    [关键词] 化疗药物；生物活性肽；抗癌；新型疗法

    [中图分类号] R151.2 [文献标识码] A [文章编号] 1673-7210(2015)08(c)-0035-05

    [Abstract] Although chemotherapy drugs have made great progress in the treatment of cancer in recent decades， the current chemotherapy drugs are still within many problems， such as the existence of toxicity， low specificity and poor resistence. Therefore， exploring new therapies has become the focus in the current. Bioactive peptide， a kind of life activities of organisms peptide compounds with special physiological functions， is made up of two to moreamino acids， and are called dipeptides or polypeptides. Diverse biological function has been found， such as immune regulation， antihypertensive， anticancer， antibacterial， anti-inflammatory and others. Its anticancer activity especially is the hot spot in the world today. In addition， the peptides have advantages to traditional chemotherapy drugs to a large extent. Also ......