宗 霞 刘 燕 王育良 张传伟

    1.南京中医药大学附属医院 江苏省中医院眼科，江苏南京 210029；2.江苏省常州市第一人民医院眼科，江苏常州 213000

    不同光环境对幼兔眼球发育的影响

    宗霞1刘燕2▲王育良1张传伟1

    1.南京中医药大学附属医院江苏省中医院眼科，江苏南京210029；2.江苏省常州市第一人民医院眼科，江苏常州213000

    目的 观察不同光环境对幼兔眼球发育的影响。方法 将24只1月龄新西兰幼兔随机分为自然光组、全光谱组与日光灯组。自然光组饲养在正常自然光线的照射环境中。全光谱组饲养在全光谱环境下。日光灯组饲养在日光灯环境下。人工光源根据外界光强度的变化自动调节照明度，使照明节律与自然光一致。饲养3个月后观察三组幼兔眼轴长度及视网膜透射电镜超微结构变化。结果 正视化过程中，三组幼兔眼轴长度均有所增加，自然光组与全光谱组增加程度比较差异无统计学意义(P>0.05)，而日光灯组增加的程度显著大于自然光与全光谱组(P<0.01)。自然光组视网膜超微结构无异常，全光谱组神经纤维层仅少量空泡化，而日光灯组视网膜损伤程度较重：感光细胞排列紊乱，线粒体肿胀；色素上皮细胞胞质出现大量脂质颗粒；神经纤维层大量空泡。结论日光灯作为光源会造成视网膜结构紊乱，对眼球发育不利。而全光谱灯对眼球发育的影响接近自然光。在眼球发育过程中应使用全光谱灯代替日光灯作为人工光源。

    视网膜；光损伤；眼轴长度；人工光源

    [Abstract]Objective To observe the effects of different light environments on eyeballs development in immature rabbits.Methods Totally 24 one-month-old New Zealand immature rabbits were randomly divided into natural light group，full spectrum group and fluorescent light group，with 8 rabbits in each group.Rabbits in natural light group were reared in sunlight environment，full spectrum group was reared in the full spectrum environment，and fluorescent light group was reared in fluorescent environment.Artificial light automatically adjust the illumination level according to changes of natural light intensity in order to be consisten twith the natural rhythm.The axial length and retinal ultrastructure under transmission electron microscopy of immature rabbits in each group were observed after threemonths. Results During emmetropization ......