赵 菁 腾梁红 凌煜玮 王亚军 海 涛 康 骅▲

    1.首都医科大学宣武医院普通外科，北京100053；2.首都医科大学宣武医院病理科，北京100053

    分化型甲状腺癌前哨淋巴结的临床病理研究

    赵菁1腾梁红2凌煜玮1王亚军1海涛1康骅1▲

    1.首都医科大学宣武医院普通外科，北京100053；2.首都医科大学宣武医院病理科，北京100053

    目的探讨检测分化型甲状腺癌前哨淋巴结(SLN)在预测颈部中央区淋巴结(CCLN)转移方面的价值。方法分析2013年1月～2015年12月首都医科大学宣武医院普外科253例分化型甲状腺癌患者，术中注射纳米炭后找到最先染色的SLN送冰冻病理，将其与CCLN术后石蜡病理进行对比，计算其阳性率。结果253例患者均在术中成功找到SLN，平均5枚/例，其中假阴性率为21.1%，阳性预测值为81.8%，阴性预测值为78.7%。SLN活检数4～5个的诊断价值最大。结论前哨淋巴结活检对于分化型甲状腺癌中央区淋巴结清扫有重要的指导意义，精准操作可以进一步提高其诊断价值。

    分化型甲状腺癌；前哨淋巴结活检；中央区淋巴结；纳米炭

    [Abstract]Objective To investigate the value of sentinel lymph node(SLN)detection in predicting the metastasis of central cervical lymph nodes(CCLN)in differentiated thyroid carcinoma.Methods 253 patients with differentiated thyroid carcinoma in Department of General Surgery，Xuanwu Hospital，Capital Medical University from January 2013 to December 2015 were analyzed.During the operation，carbon nanoparticles were injected and then to detect SLN which stained firstly by frozen pathology.Compared this results with the routine histopathology results of CCLNs and calculated the positive rate.Results The detection rate of SLN was 100%and the average number of SLN was 5.The false negative rate ......