殷冬梅+阮祥燕++Alfred+O+Mueck

    [摘要] 目的 研究非肥胖多囊卵巢综合征(PCOS)患者的临床特征及糖脂代谢的特点。 方法 选择2014年11月～2016年3月在首都医科大学附属北京妇产医院妇科内分泌门诊就诊的74例非肥胖PCOS患者作为研究组，同期45例年龄和体重指数相匹配的健康女性作为对照组。测量所有受试者的临床特征；测定血清性激素水平及代谢参数；采用稳态模型评估的胰岛素抵抗指数；比较两组上述各项指标的差异。 结果 PCOS组患者腰臀比、血清总睾酮、促黄体生成素水平、促黄体生成素/卵泡刺激素比值及血清低密度脂蛋白胆固醇均高于对照组(P < 0.01或P < 0.05)；载脂蛋白A浓度低于对照组，差异有高度统计学意义(P < 0.01)。 结论 非肥胖PCOS患者同样存在代谢异常，临床上应引起重视。

    [关键词] 多囊卵巢综合征；非肥胖；腰臀比；胰岛素抵抗；脂代谢

    [中图分类号] R711.7 [文献标识码] A [文章编号] 1673-7210(2016)10(c)-0103-04

    [Abstract] Objective To investigate the clinical features and metabolism characteristics of patients with non-obese polycystic ovary syndrome. Methods From November 2014 to March 2016， 74 patients with non-obese PCOS who visited the Department of Endocrinology of Beijing Obstetrics and Gynecology Hospital， Capital Medical University were enrolled as the study group， and 45 age-matched healthy women in the same period were included as the control group. Clinical characteristics ......