赵雷+姚丽艳+朱晓玉

    [摘要] 目的 探讨凝血纤溶指标与先兆流产妊娠结局的相关性。 方法 选择2014年12月～2015年12月在新疆医科大学第二附属医院妇产科确诊为先兆流产患者78例，经治疗后有41例患者继续妊娠，为继续妊娠组；37例患者发展为难免流产，为难免流产组；另选取40例正常妊娠患者为对照组。检测并比较各组孕妇静脉血纤维蛋白原(Fbg)、D-二聚体(DD)和血小板(PLT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)水平差异。 结果 难免流产组PLT、DD、Fbg水平明显高于继续妊娠组和正常妊娠组，差异有统计学意义(P 0.05)。 结论 凝血纤溶失衡与先兆流产患者不良妊娠结局相关，其对先兆流产妊娠结局的影响主要发生在孕龄≥12 周。复发性流产患者更容易出现凝血纤溶失衡。

    [关键词] 先兆流产；凝血纤溶；妊娠结局

    [中图分类号] R714.21 [文献标识码] A [文章编号] 1673-7210(2016)10(c)-0111-04

    [Abstract] Objective To study the relationship between the blood coagulation fibrinolysis and threatened abortion outcomes. Methods From December 2014 to December 2015， 78 cases who were diagnosed as threatened abortion patients in the Second Affiliated Hospital of Xinjiang Medical University were selected， among those patients 41 cases of continue pregnancy after treated were set as the continue pregnancy group； and the other 37 patients developed inevitable abortion were set as inevitable abortion group. 40 cases of normal pregnancy were selected as control group. The levels of Fbg ......