体外受精长效长方案促排卵周期卵泡冲洗对患者胚胎发育的影响
荆霞 冯忠海 韦冰[摘要] 目的 探讨长效长方案促排卵周期中,冲洗卵泡对患者胚胎发育情况影响。 方法 回顾性分析2014年 7月~2016年6月在广东医科大学附属医院生殖中心接受长效长方案试管婴儿(IVF)助孕的343例女性的临床资料,其中采用卵泡冲洗99例(冲洗组),采用直接吸取卵泡液244例(对照组)。对两组患者获卵率、正常受精(2PN)卵率、2PN卵裂率、优胚率、囊胚率、胚胎可利用率、临床妊娠率、着床率和流产率进行分析。 结果 在长效长方案促排卵周期中,冲洗组的卵裂胚胎利用率、优胚率、囊胚冷冻率均显著高于对照组,差异有统计学意义(P 0.05)。 结论 在长效长方案促排卵周期中,冲洗卵泡并不能使获卵率增加,但能有效提高卵裂胚胎的利用率,优胚率和囊胚冷冻率,患者临床妊娠率和种植率均有增高趋势。
[关键词] 卵泡冲洗;胚胎发育;妊娠结局
[中图分类号] R713.7 [文献标识码] A [文章编号] 1673-7210(2017)08(a)-0059-04
[Abstract] Objective To evaluate the effects of follicle flushing on embryonic development in patients of long protocol controlled ovarian hyperstimulation in vitro fertilization. Methods From July 2014 to June 2016, in Reproductive Medicine Center, Affiliated Hospital of Guangdong Medical University, the clinical data of 343 patients underwent in vitro fertilization (IVF) were analyzed retrospectively. Among them,99 patients treated with G-MOPs were set as follicle flushing group, and 244 patients sucked direethy folliculer fluid were as control group. The oocyte retrieval rate, fertilization rate, 2PN cleavage rate ......
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