徐文 曹辉 杨远荣

    [摘要] 人参皂苷Rh2是从红参中提取得到的一种二醇型低糖链皂苷单体，也是人参中主要活性成分之一。人参皂苷Rh2因其代谢作用多样性，药学工作者在深入研究过程中发现其具有多种药理活性，尤其在抗肿瘤活性方面表现显著，取得了一定的进展。作者通过查阅国内外近年来大量文献，从抗肿瘤、改善心肌缺血、抗子宫内膜异位症、抗过敏、调节免疫功能、防辐射、抗哮喘及抗抑郁等方面对人参皂苷Rh2的药理活性与作用机制进行分析和归纳，并进行综述，以期为药学工作者更深入的研究和开发利用人参皂苷Rh2提供参考。

    [关键词] 人参皂苷Rh2；皂苷单体；药理活性；作用机制

    [中图分类号] R285 [文献标识码] A [文章编号] 1673-7210(2017)10(a)-0042-04

    [Abstract] Ginsenoside Rh2 has be extracted from red ginseng as a diol-based low-sugar saponin monomer and one of the main active ingredients in ginseng. Ginsenoside Rh2 is discovered that it has a variety of pharmacological activity by pharmacy workers in the depth of the study ， and was made some progress especially in anti-tumor activity. the pharmacological effects of ginsenoside Rh2 are analyzed and summarized by The authors from a lot of literature at home and abroad on the aspects of anti-tumor， improving myocardial ischemia， anti-endometriosis， anti-allergy， immune function， radiation protection， anti-asthma and antidepressant activity and mechanism of action， this review studies and develops the use of ginsenoside Rh2 in order to provide reference. ......