郭婷 何虹 胡丰阳 梅孟雪 刘佩蓉

    [摘要] 目的 探讨复方黄柏液治疗卡培他滨所致手足综合征的效果。 方法 选取2017年1月～2018年3月南昌大学第二附属医院肿瘤科80例手足综合征患者为研究对象，采用随机数字表法将其分为试验组与对照组，每组各40例。试验组采用复方黄柏液湿敷，对照组给予自配液湿敷，每天湿敷前，先使用生理盐水清洗伤口，再用无菌纱块浸渍后进行湿敷，30 min后取下纱块，3次/d。治疗1周后，观察患者手足综合征分级变化、治疗效果、症状改善情况，利用皮肤敏感值-16(Skindex-16)量表对患者的生活质量进行评估。 结果 干预后，试验组手足综合征分级变化明显优于对照组，总有效率显著高于对照组，Skindex-16得分、症状评分均显著低于对照组，差异均有统计学意义(P < 0.05)。 结论 复方黄柏液湿敷治疗卡培他滨所致手足综合征效果较好，能有效改善患者症状，提高患者生活质量。

    [关键词] 复方黄柏液；卡培他滨；手足综合征

    [中图分类号] R248 [文献标识码] A [文章编号] 1673-7210(2018)09(b)-0125-04

    [Abstract] Objective To explore the therapeutic effect of Compound Cortex Phellodendri Liquid in the treatment of Capecitabine-induced hand-foot syndrome. Methods Eighty cases of patients with hand-foot syndrome in the Department of Oncology of a triple-A general hospital in Nanchang City from January 2017 to March 2018 were selected as research objects， and they were divided into the experimental group and the control group by random number table method， with 40 cases in each group. The experimental group was given hydropathic compress with Compound Cortex Phellodendri Liquid， and the control group was was given hydropathic compress with self-made liquid. Before hydropathic compress ......