凌琦 吴永定 秦国强

    [摘要] 目的 研究五类水果与膀胱癌发病率的关系。 方法 2005年9月～2012年6月，采用多中心病例对照研究方法，在广州市第一人民医院、中南大学附属第二医院、华中科技大学同济医学院附属同济医院、浙江大学附属第一医院共招募432例膀胱癌患者和392例非膀胱癌患者，将膀胱癌患者作为实验组，非膀胱癌患者作为对照组，分别对两组患者进行问卷调查，收集数据后进行统计分析。 结果 实验组问卷应答率及问卷有效率分别为99.1%、100.0%，对照组问卷应答率及问卷有效率分别为99.5%、100.0%;食用柑橘类水果≥2次/周或可显著降低膀胱癌的发病风险(P < 0.05)。 结论 多食用柑橘类水果或许有助于降低膀胱癌发生的风险。

    [关键词] 膀胱癌;发病率;病例对照研究

    [中图分类号] R737.14? ? ? ? ? [文献标识码] A? ? ? ? ? [文章编号] 1673-7210(2019)02(c)-0045-04

    [Abstract] Objective To study the relationship between five kinds of fruits and the incidence of bladder cancer. Methods A multicenter case-control study was conducted from September 2005 to June 2012. Four hundred and thirty-two cases of bladder cancer and 392 cases of non bladder cancer were recruited in Guangzhou First People′s Hospital， the Second Affiliated Hospital of Central South University， Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology and the First Affiliated Hospital of Zhejiang University. Patients with bladder cancer were classified as experimental group ......