李燕明 黄娜娜 何淑玲

    [摘要] 目的 探讨养阴舒肝胶囊联合枸橼酸氯米芬治疗多囊卵巢综合征(PCOS)伴不孕症的效果。 方法 选取2016年2月～2018年2月中山市中医院收治的PCOS伴不孕症患者83例为研究对象。采用随机数字表法将患者分为对照组(n = 41)和实验组(n = 42)。对照组给予枸橼酸氯米芬治疗，实验组给予养阴舒肝胶囊联合枸橼酸氯米芬治疗。比较两组患者治疗后临床疗效、排卵、妊娠结局以及卵巢过度刺激综合征(OHSS)发生率;比较两组治疗前后血清激素[雌二醇(E2)、促卵泡激素(FSH)、促黄体激素(LH)]水平;记录两组患者治疗期间不良反应发生情况。 结果 实验组临床总有效率(76.19%)显著高于对照组(46.34%)(P 0.05)。两组患者不良反应发生率比较差异无统计学意义(P > 0.05)。 结论 养阴舒肝胶囊联合枸橼酸氯米芬治疗PCOS伴不孕症患者，疗效显著，可改善患者血清激素水平，提高排卵率、妊娠率，且不增加不良反应，具有一定的临床应用价值。

    [关键词] 养陰舒肝胶囊;枸橼酸氯米芬;多囊卵巢综合征;不孕症;临床研究

    [中图分类号] R711.75 ? ? ? ? ?[文献标识码] A ? ? ? ? ?[文章编号] 1673-7210(2019)05(b)-0071-04

    [Abstract] Objective To explore the clinical effect of Yangyin Shugan Capsules combined with Clomiphene Citrate in the treatment of polycystic ovary syndrome(PCOS) associated with infertility. Methods A total of 83 PCOS associated with infertility admitted in Zhongshan Hospital of Traditional Chinese Medicine from February 2016 to February 2018 were selected as the research subjects. Patients were divided into control group (n = 41) and experimental group (n = 42) according to the random number table method. The control group was treated with Clomiphene Citrate and the experimental group was treated with Yangyin Shugan Capsules combined with Clomiphene Citrate. The clinical efficacy ......