郑丽娟 李慧 苏敏仪

    [摘要] 目的 观察五行音乐联合认知心理辅导对晚期妊娠合并抑郁症的疗效，并探讨其对孕妇睡眠质量、血清孕激素和孕激素诱导阻断因子(PIBF)的影响。 方法 选取2017年3月～2019年3月广东省妇幼保健院产科门诊收治的晚期先兆流产孕妇120例，根据随机数字表法分为常规治疗组(对照组，60例)和五行音乐联合认知心理干预治疗组(观察组，60例)。治疗2周后，比较两组宫缩消失时间、延长妊娠周数和治疗有效率。比较治疗前后匹兹堡睡眠质量评分(PSQI)、抑郁自评量表(SDS)、血清孕酮水平和PIBF浓度的变化。 结果 两组患者年龄、孕龄、孕次、产次和SDS评分比较，差异无统计学意义(P > 0.05)。观察组较对照组宫缩消失更早，妊娠延长周数更长，治疗有效率更高(P 0.05)，观察組治疗后的PSQI评分较治疗前降低，睡眠良好孕妇比例升高(P 0.05)。治疗2周后，两组孕妇的孕酮和PIBF水平较治疗前明显升高，观察组的孕酮和PIBF水平较对照组更高(P 0.05). Compared with the control group， contractions disappeared earlier in the observation group， gestation was prolonged longer， and treatment efficiency was higher (P 0.05). The PSQI score in the observation group after treatment was lower than that before treatment， and the proportion of pregnant women with good sleep was higher (P 0.05). After 2 weeks of treatment， the levels of progesterone and PIBF in the two groups of pregnant women were significantly higher than those before treatment ......