彭拥军 蒋星卓 李文倩 吴旭 朱冰梅

    [摘要] 变应性鼻炎(AR)是机体接触过敏原后，主要由免疫球蛋白E(IgE)介导的一种常见的变态反应性疾病。针灸作为治疗AR的一种常见疗法，具有安全、有效、副作用小等优势。本文通过文献检索，回顾、总结及探讨AR的发病机制和针灸治疗作用机制的研究进展。研究显示AR的发生主要和免疫、神经功能紊乱及鼻黏膜炎性细胞浸润有关，而针灸可通过免疫调节、神经调节、降低IgE、减少鼻黏膜炎性浸润等途径发挥治疗作用。同时指出目前研究中的问题和不足，为进一步研究提供思路。

    [关键词] 变应性鼻炎;针灸;免疫调节;神经调节

    [中图分类号] R765.2 ? ? ? ? ?[文献标识码] A ? ? ? ? ?[文章编号] 1673-7210(2020)04(c)-0061-04

    Mechanism of acupuncture in the treatment of allergic rhinitis

    PENG Yongjun1 ? JIANG Xingzhuo1 ? LI Wenqian1 ? WU Xu1 ? ZHU Bingmei2

    1.Department of Acupuncture and Moxibustion， Affiliated Hospital of Nanjing University of Chinese Medicine， Jiangsu Province， Nanjing ? 210029， China; 2.Center for Regenerative Medicine， West China Hospital， Sichuan University， Sichuan Province， Chengdu ? 610041， China

    [Abstract] Allergic rhinitis (AR) is a common non-infectious chronic inflammatory disease of the nasal mucosa mediated by immunoglobulin E (IgE) when body is exposed to allergens. Acupuncture， as a common treatment for AR， has the advantages of safety， effectiveness， and few side effects. This review summarized and discussed the progress of the pathogenesis of AR and the mechanisms of acupuncture treatment by retrieving relevant literatures in recent years. The mechanisms underlying AR are complex ......