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淋巴瘀滞对自体肾移植影响的实验研究(2)
http://www.100md.com 2008年9月5日 《中国实用医药》 2008年第24期
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    【Abstract】 Objective To search for the influence of lymph stasis on autologous renal transplantation.Methods Totally 16 rabbits were selected,left renes were used to established the models of autologous renal transplantation and models of lymph stasis,right renes as compared with the left renes were used to established the models of autologous renal transplantation only.The specimens were obtained from the bilateral renes after 4、7、14、28 days,formalin-fixed,paraffin-embedded section,HE staining.Results The surrounding tissue of the left renes edema,adhesion,with the time after the operation,edema reduced,but adhesion increased.Bilateral renal glomeruli and tubules no obvious changes.The fourth day after the operation,lymphatic capillaries between lobule of the lymph stasis renes were obviously expansion,lymph deposition,mesenchyma showed multifocal lymphocytic infiltration with edema.The seventh day after the operation,in addition to the above changes,lymphocyte infiltration and edema of the mesenchyma were most obviously.The fourteenth day after the operation,lymphatic capillaries between lobule gets atrophy,mesenchyma showed few lymphocytic infiltration.The 28 days after the operation,lymphatic capillaries atrophy sharply,accompanied by glomeruli capillary congestion.Conclusion Lymph stasis of autologous renal transplantation had a certain impact to the histology,and it may be the important factors to cause the acute and chronic rejection after renal transplantation. ......
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