益气复胰汤汤剂与中药配方颗粒化学成分的对比研究(1)
【摘要】 目的 对益气复胰汤传统汤剂与中药配方颗粒有效成分(或指标成分)的含量进行测定,探讨益气复胰汤中药配方颗粒在中药复方配伍中应用的可行性。方法 采用高效液相色谱方法,对益气复胰汤汤剂与中药配方颗粒中黄芪甲苷、芍药苷和延胡索乙素等指标成分进行含量测定。结果 益气复胰汤1号汤剂与中药配方颗粒中的黄芪甲苷含量分别为0.031%和0.039%；益气复胰汤2号汤剂与中药配方颗粒中的芍药苷含量分别为0.41%和0.39%；益气复胰汤3号汤剂与配方颗粒中的延胡索乙素含量分别为0.011%和0.016%。结论 两者主要指标成分的含量差异无统计学意义,为中药配方颗粒在中药复方配伍中的应用提供了实验依据。【关键词】 益气复胰汤；中药配方颗粒；高效液相色谱法
Comparison study with chemical constituents in formula granule and decoction of Yiqifuyi decoction
LIU Zhi-cheng，CHEN Qi-chang，CHEN Jun，et al.Department of Pharmacy，Chinese Medicine Hospital in Shenzhen City，Guangdong 518028,China
【Abstract】 Objective To determine the content of traditional decoction of Yiqi fuyi and the traditional Chinese medicine formula granules,approached the feasibility of use the Yiqi fuyi prescription drug granules in Chinese medicine complex compatibility.Methods The HPLC method was used to detect the content of astragaloside,paeoniflrin and tetrahydropalmatine both in Yiqi fuyi decoction and formula granulas.Results The content of astragali in Yiqi fuyi number and the formula granules are 0.031%and 0.039%,the content of peoniflorin in Yiqi fuyi number 2 and the formula granules are 0.41%and 0.39%,and the content of tetrahydropalmatine in Yiqi fuyi number 3 and the formula granules are 0.011%and 0.016%.Conclusion The content of the main index ingredients inYiqifuyi decoction and the formula granules have no significant diffrence.It has made foundation for the use of formula granules on clinic. ......
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