IL-6，Fas与慢性阻塞性肺疾病急性加重期的相关性研究(1)
 |
【摘要】 目的 探讨白介素-6(IL-6)与凋亡因子(Fas)在慢性阻塞性肺疾病急性加重期中的作用与意义及二者的相关性。方法 用ELISA方法检测35例慢性阻塞性肺疾病急性加重期患者和32例健康对照组血清中IL-6和Fas的水平。结果 慢性阻塞性肺疾病急性加重期中IL-6与Fas的水平均显著高于对照组，差异具有显著性意义(P<0.05)。结论 Fas介导COPD患者的免疫细胞凋亡，IL-6与Fas共同参与了COPD的气道炎性反应，对判断COPD的急性加重及呼吸功能具有重要的临床意义。
【关键词】慢性阻塞性肺疾病；Fas/FasL；IL-6
IL-6，Fas and chronic obstructive pulmonary disease with acute exacerbation of the relevance
LIU Yan-hong,XIA Xi-zheng.Department of Respiratory Medicine,Secomd affiliated Hospital of Zhengzhou University,Henan 450000,China
【Abstract】 Objective To investigate the implication and correlation of serum IL-6 and Fas/Fasl ligand in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods The levels of serum IL-6 and Fas/FasL in 35 patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)and32 healthy control subjects were detected by ELISA.Results The levels of serumFas and IL-6 inpatients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD) were significantly higher than those in healthy control subjects ......
您现在查看是摘要页，全文长 4389 字符。