低剂量吉西他滨联合顺铂治疗老年晚期非小细胞肺癌的临床观察
 |
| 第1页 |
参见附件。
【摘要】 目的观察低剂量吉西他滨联合顺铂治疗老年晚期非小细胞肺癌的疗效及毒副反应。方法 国产吉西他滨 800 mg/m2,静脉滴注30 min,第1、8天;顺铂14 mg/m2,第1~5天,3周重复,治疗32例70岁以上的晚期非小细胞肺癌患者。结果 32例患者共化疗108周期,完全缓解0,部分缓解17例(53.1%,17/32),稳定8例(25%,8/32),进展7例(21.9%,7/32),总有效率53.1%,疾病控制率(CR+PR+SD)78.1%,中位疾病进展时间5.2个月,中位生存期11.6个月。毒副作用主要为粒细胞减少、血小板下降、贫血、乏力。均可耐受。结论 低剂量吉西他滨联合顺铂治疗老年晚期非小细胞肺癌的疗效肯定且患者耐受性较好。
【关键词】非小细胞肺癌;老年患者;吉西他滨;顺铂;低剂量
Observation of low-dose Gemcitabine combined with Cisplatin in treating elderly patients with non-small-celllungcancer
ZHANG Chun-zhen ,SHI Chao-sheng ,XIA Jin.Medical-department of Anyang Tumor Hospital, Anyang 455000,China
【Abstract】 Objective To evaluate the efficacy and toxicity of low-dose gemcitabine combined with cisplatin in elderly patients with advanced non-small-cell lung cancer. Methods Thirty-two elderly patients with advanced non-small-cell lung cancer were treated with gemcitabine 800 mg/m2 ond1、8,cisplatin 14 mg/m2on d1-5.The regimen was repeated every 21 days. All patients received two or more cycles.Results Thirty-two patients were evaluated after 2 to 6 cycles of chemotherapy ......
您现在查看是摘要介绍页，详见PDF附件。