抗精神病药致恶性综合征临床分析与治疗探讨(1)

http://www.100md.com 2010年3月15日 《中国实用医药》2010年第8期

     【摘要】 目的 探讨恶性综合征的临床特点与治疗,提高临床工作者对本综合征的认识。方法 对18例NMS患者进行临床评价。结果 ①18例患者均有肌强直、高热、意识障碍、肌酸激酶值增高 ②发病3 d 内确诊并及时治疗者10例,全部存活,1周内未得到确诊者2例 ,全部死亡。结论 NMS以肌强直、发热、意识障碍、肌酸激酶值增高为主要特征。 避免误诊、早诊断早治疗是提高生存率的关键所在。

    【关键词】恶性综合征; 临床特点; 误诊; 治疗

    Clinical analysis and treat of neuroleptic m alignant syndrome

    LU Ling, CHEN Min,LI Jing-yang,et al.Department of Neurology,the First Affiliated Hospital of south of China University,Hengyang 421001,China

    【Abstract】 Objective To improve undertanding NMS through studing the clinical features and treatment of neuroleptic m alignant syndrome[NMS].Methods 18 NMS patients were assessed.Results ①All the 18 patients had the manifestation of hyperthermia, muscle rigidity, consciousness disorder and increased CK level;②10 patients were correctly diagnosed and treated within the 3 days after the onset and survived; the 2 patients who did not get a correct diagnosis during the first week died.Conclusion NMS is mainly characterized by muscle rigidyty, hyperthemia, consciousness disorder and increased CK level; avoiding misdiagnosis and early treatment are the key of survival rate. ......