速度向量成像技术对川崎病冠状动脉瘤左心室纵向及径向收缩功能的研究(1)
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【摘要】 目的 应用速度向量成像技术定量评价川崎病冠状动脉瘤患儿左心室纵向及径向收缩功能。方法 37例川崎病冠状动脉瘤患儿根据冠状动脉瘤大小分为病变Ⅰ组、Ⅱ组,分别与20例正常儿童对照,采用速度向量成像技术分别测量左心室最大纵向及径向运动速度、应变及应变率;Simpson法心内膜自动跟踪测量左心室射血分数、每搏量。结果 病变Ⅰ组各节段左心室最大纵向运动速度及应变率明显低于对照组(P<0.05),径向应变率明显低于对照组(P<0.05);病变Ⅱ组各节段最大纵向运动速度、应变及应变率均明显低于Ⅰ组(P<0.05),径向应变率明显低于Ⅰ组(P<0.05);各组间左心室射血分数、每搏量差异均无统计学意义。结论 川崎病冠状动脉瘤患儿左心室最大纵向运动速度及纵向、径向应变率明显减低,提示心肌收缩功能受损,速度向量成像技术可以定量评价左室局部收缩功能。
【关键词】
超声心动描记术;黏膜皮肤淋巴结综合征;冠状动脉瘤;左心室功能
Quantitative Assessment of Left Ventricular Longitudinal and Radial Systolic Function in Kawasaki Disease with Coronary Aneurysms using Velocity Vector Imaging
GE Yan, HUANG Mei-rong. Department of Ultrasound, The First Affiliated Hospital of Xiamen University,Xiamen 361003, China
【Abstract】 Objective To explore the value of velocity vector imaging (VVI) in detecting left ventricular longitudinal and radial systolic function in Kawasaki Disease (KD) with coronary aneurysms. Methods Thirty seven children with KD coronary aneurysms were divided into two groups (GI & GⅡ) according to their size of lesions, and twenty healthy subjects as the control group. The left ventricular longitudinal and radial systolic peak velocities (Vs), systolic peak stain (ε) and systolic peak stain rate (SRs) of each segment were analyzed by VVI. The left ventricular ejection fraction (EF) and stroke volume (SV) were measured by Simpson method of automatic tracking endocrinal. Results longitudinal Vs， SRs and radial SRs of G I were significantly lower (P<0.05) than that of the control， longitudinal Vs, SRs，ε and radial SRs of G Ⅱ were lower (P<0.05) than that of G I. There was no significant difference in EF, SV among three groups. Conclusion VVI was a useful method which can detect impaired regional left ventricular systolic function in KD with coronary aneurysms.
【Key words】 Echocardiography; Mucocutaneous lymph node syndrome; Coronary aneurysms; Left ventricular function.
川崎病中小血管炎可引起心肌炎性病变及心肌损伤、冠状动脉扩张、冠状动脉瘤,甚或导致冠状动脉血栓、狭窄并发心肌梗死[1]。本研究运用速度向量成像技术(velocityvectorimaging,VVI)定量检测川崎病冠状动脉瘤患儿左心室心肌各节段长轴及短轴方向最大运动速度(Vs)、应变(ε)、应变率(SRs)与正常组对照,用以定量评价川崎病冠状动脉瘤患儿左心室纵向及径向收缩功能。
1 资料与方法
1.1 一般资料
选取临床根据1984年日本川崎病研究委员会制定的标准[1]诊断川崎病冠状动脉瘤患儿37例,其中男28例,女9例,年龄3个月~8岁,平均(3.7±2.7)岁,平均心率(109±34)次/min,对照组选取健康体检幼儿20例,男12例,女8例,年龄3个月~7岁,平均(3.6±2.1)岁,平均心率(107±25)次/min。1.2 仪器与方法
采用AcusonSequioa512型彩色超声诊断仪,探头频率3 ......
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