银杏达莫注射液治疗急性脑梗死临床研究(1)
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【摘要】 目的 探讨银杏达莫注射液治疗急性脑梗死中的疗效。方法 将2006年3月至2009年2月就诊于我院的急性脑梗死患者108例，随机分为对照组与治疗组，各54例。治疗组在常规治疗的基础上给予银杏达莫注射液20 ml加入5%葡糖糖注射液250 ml静脉滴注 1次/d，对照组在常规治疗的基础上给予复方丹参注射液20 ml加入5%葡糖糖注射液250 ml静脉滴注 1次/d，均应用14 d，观察其临床疗效及不良反应。结果 治疗组总有效率为87.0%，对照组总有效率为70.1%，(χ2=4.475，P<0.05)，两组间比较差异有统计学意义。用药前后两组均无不良反应发生，肝肾功能无明显变化。结论 银杏达莫注射液治疗急性脑梗死有良好疗效，较为安全。
【关键词】 银杏达莫注射液；急性脑梗死
Clinical observation of yinxingdamo injection in the treatment of acute cerebral infarction of 54 cases
SUN Guangbin，LI Fengjun.Department of Neurology,People's Hospital of Yanggu County,Shandong 252300,China
【Abstract】 Objective To investigate the efficacy of Yinxingdamo injection in the treatment of acute cerebral infarction.Methods 108 patients with acute cerebral infarction in our hospital were randomly divided into control group and treatment group,54 patients per group.The treatment group received Yinxingdamo injection 20 ml+5%glucose infusion 250 ml intravenous drip qd on the basis of routine treatment.The controlgroup received Fufangdanshen injection 20 ml+5%glucose infusion 250 ml intravenous drip qdon the basis of routine treatment.14 days were a course.The clinical efficacy and adverse reactions were observed.Results The total effective rate was 87.0%in the control group,the total effective rate was 70.1% (χ2 = 4.475,P<0.05),there were significant differences between the two groups.There were no adverse reactions before and after treatment occurred,no significant changes in liver and kidney function.Conclusion The effect of Yinxingdamo injection for acute cerebral infarction, is a safe and satisfactory method.
【Key words】 Yinxingdamo injection; Acute cerebral infarction; Adverse reactions
脑梗死是中老年常见的神经内科疾病，约占脑血管疾病的75%，其致残率较高。银杏达莫注射液为国产第4代银杏叶提取物(cinkgobilohaextract，GbE)及双密达莫的复合制剂，已应用于治疗脑血管疾病，并取得一定疗效。我院2006年3月至2009年2月应用银杏达莫注射液治疗急性脑梗死54例，取得了较好的临床效果。现报告如下。
1 资料与方法
1.1 一般资料 选取2006年3月至2009年2月就诊于我院的符合标准的急性脑梗死患者108例，随机分为对照组与治疗组，各54例。对照组：男34例，女20例；年龄43~72岁，平均60.5岁；CT示脑梗死部位：脑叶梗死22例，丘脑梗死17例，基底节梗死13例，脑干梗死2例。治疗组：男36例，女18例；年龄40~75岁，平均62.4岁；CT示脑梗死部位：脑叶梗死24例，丘脑梗死16例，基底节梗死13例，脑干梗死1例。两组间性别、年龄、病变部位及严重程度等差异均无统计学意义(P>0.05)，具有可比性 ......
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