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腰椎结核术式及血沉对手术疗效的探讨(1)
http://www.100md.com 2011年5月25日 刘延雄 李梅 郭龙 袁玮
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     【摘要】 目的 探讨腰椎结核术式及血沉对手术疗效的影响。方法 回顾性分析21例侧前方入路清除病灶、后路内固定以及植骨融合手术,联合药物治疗对腰椎结核患者后凸Cobbs角和神经系统功能Frankel分级的影响;探讨不同血沉对手术疗效的影响。结果 所有患者手术切口均一期愈合,血沉2周内恢复正常,植骨于6~9个月融合。术后腰椎后凸Cobbs角(8.3 ± 2.4)°较术前(21.3 ± 4.6)°明显减小(P<0.01),神经系统功能Frankel分级明显改善。血沉60 mm/h组与血沉60~85 mm/h组在手术时间、术中出血量、术后引流量及Cobbs角等方面均差异无统计学意义(P>0.05)。结论 侧前方入路清除病灶、后路内固定以及植骨融合术是治疗腰椎结核的有效方法;血沉85 mm/h不是手术绝对禁忌证。

    【关键词】 腰椎结核;后前路联合;植骨;内固定;血沉

    Effects of blood sedimentation rate (BSR)-associated operation methods on lumbar vertebra tuberculosis

    LIU Yan-Xiong, LI Mei, GUO Long, et al.Department of Orthopedics, Affiliated Hospital of Yanan University; Centreal Hospital for Staff of Yanchang Petroleum, Yanan 716000, China

    【Abstract】 Objective To explore the operation methods of lumbar vertebra tuberculosis, and to investigate the effects of blood sedimentation rate (BSR) on operative effect. Methods Twenty-one patients with lumbar vertebra tuberculosis received operation of anterior debridement, bone grafting and internal fixation in addition to drug administration. Cobbs angle and Frankel grade system for evaluate the neurological deficits were compared between pre-operation and post-operation. Additionally, operative effect on patients with different BSR was studied. Results Operative incisions of 21 cases were primary healing, BSR was normalized within 2 weeks, and grafting bones were fused within 6~9 months. The Cobbs angle was significantly reduced, and the Frankel grade was generally improved after operation compared with pre-operation[Cobbs angle: post-operation (8.3 ± 2.4)°, VS. pre-operation (21.3 ± 4.6)°, P<0.05]. No difference of operation time, blood lose, postoperative drainage, or Cobbs angle could be detected between BSR 60 mm/h group and BSR 60~85 mm/h group (P>0.05). Conclusion Lumbar vertebratuberculosis treated with operation methods of anterior debridement, bone grafting and internal fixation contribute to spinal stability. Patients with BSR at 85 mm/h can not be excluded from operation.

    【Key words】 Lumbar vertebra tuberculosis; Anterior and posterior operation; Bone grafting; Internal fixation; Blood sedimentation rate ......

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