盐酸氨溴索丹参酮ⅡA磺酸钠时辰疗法雾化吸入佐治毛细支气管炎疗效观察(1)
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【摘要】目的探讨盐酸氨溴索(沭舒坦)和丹参酮ⅡA磺酸钠时辰雾化吸入佐治小儿毛细支气管炎的疗效。方法将128例小儿毛细支气管炎患儿随机分成两组，其中对照组64例，给予抗病毒、吸氧、平喘、祛痰止咳、维持水电介质平衡等对症综合处理，治疗组64例在对照组基础上加用盐酸氨溴索75 mg(沭舒坦1 ml)加生理盐水2 ml，丹参酮ⅡA磺酸钠注射液02 mg(kg•d)加生理盐水4 ml，由空气压缩泵雾化，采用“时辰疗法”(即晨起和睡前进行雾化)分别进行雾化吸入，每次10 min，2次/d，疗程3~7 d，丹参酮ⅡA磺酸钠注射液06 mg(kg•d)加至5%葡萄糖注射液50~100 ml静脉滴注，1次/d，疗程3~7 d。对两组进行疗效比较。结果治疗组64例，治愈48例，治愈率75%，较对照组治愈14例，治愈率219%，χ2=3406，P<001有显著性差异。治疗组患儿体温复常、气促减轻、喘憋消失、哮鸣音消失、咳嗽缓解、啰音消失等的时间和住院天数较对照组明显缩短。结论盐酸氨溴索丹参酮ⅡA磺酸钠时辰疗法雾化吸入联合丹参酮ⅡA磺酸钠注射液06 mg(kg•d)静脉滴注佐治小儿毛细支气管炎、安全、有效，快速缓解症状和体征，提高治愈率。缩短了患儿住院天数。
【关键词】盐酸氨溴索；丹参酮ⅡA磺酸钠；毛细支气管炎；时辰雾化
Effects of chronotherapy of the inhalation of the Ambroxol Hydrochloride and Sodium Tanshinon ⅡAsilate for Injection on bronchiolitisWEN Yanhua, ZONG Chuanhui Central Hospital of Caodian Town of Baoying Country Jiangsu, 225803,China
【Abstract】ObjectiveProbe into effects of the inhalation of the Ambroxol Hydrochloride and Sodium Tanshinon ⅡAsilate for Injection on bronchiolitis MethodsIn cluded in this study were 128 cases with children bronchiolitis randomized divied into two groups, with 64 in each groupThe 64 cases in the control group (CG) were synthesized on the antiviral,Oxygen uptake,Prevent asthma,Expelling phlegm and arresting coughing,kept the water and the dielectricin balanced and so on, on the basic of the CG, the other 64 patients in the experimental group (EG) were given the Ambroxol Hydrochloride 75 mg in 2 ml normal saline(NS),Sodium Tanshinon ⅡA silate 02 mg(kg•d) in 4 ml NS,used the air compressor pump to atomize inhaled via chronotherapy, every time 10 minutes, twice a day, for a course of 3 ~7 days; Sodium Tanshinon ⅡAsilate 06 mg(kg•d) in 5% glucose injection (50~100 ml),iv gtt, qd, for a course of 3 ~7 days Contrasting the curative effect between the two groups ResultsThere 48 cases(75%)were cured and 5 cases(78%) ineffective in EG Vith a total eriective rate of 922%,while there were only 14 cases(219)were cures and 24 cases(375%) ineffective,with a total effective rate of 625% in the CGThere was a statistically significantdifference in the total effective rate between them(P<001) ......
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