血清维生素A与儿童1型糖尿病的相关性探讨(1)
【摘要】 目的 初步探讨血清维生素A水平与儿童1型糖尿病(T1DM)关系，了解糖化血红蛋白(HbA1c)、血清空腹C-肽与血清维生素A的相关性。方法 选取32例T1DM患儿为T1DM组，28例健康体检儿童为对照组，用微量荧光方法检测两组血清维生素A水平，用化学发光法、激光散射比浊法分别测定32例T1DM患儿血清C-肽、HbA1c。结果 T1DM组血清维生素A水平明显低于对照组(P<0.01)；T1DM组血清维生素A水平与空腹血清C-肽水平呈正相关(r=0.356, P<0.05)，与HbA1c呈负相关(r=-0.394, P<0.05)。结论 T1DM患儿体内存在维生素A缺乏，维生素A水平低下可能与T1DM的发生有关。【关键词】
维生素A；糖尿病；1型；儿童
The relationship between serum concentration of vitamin A and type 1 diabetes mellitus in children
CHEN Yong-xing, WEI Hai-yan, LI Chun-zhi, et al.
Department of Endocrinology of Zhengzhou Childerns Hospital, Zhengzhou 450052,China
【Abstract】 Objective
To explore the relationship between serum concentration of vitamin A and type 1 diabetes mellitus in children. Methods Totally 32 children with T1DM were taken as T1DM group, and 28 healthy children as normal control group. The serum concentration of vitamin A was determined by the method of micro-flourescence, and the serum level of C-peptide and the level of HbA1c were determined by the methods of chemoluminescence and laser nephelometry ......
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