抗痨胶囊在老年初治涂阳肺结核强化期治疗的应用(1)
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【摘要】 目的 探讨抗痨胶囊在老年初治涂阳肺结核强化期治疗的疗效。方法 选取我院老年初治涂阳肺结核患者110例，分为观察组(异烟肼、利福喷丁、乙胺丁醇、左氧氟沙星、抗痨胶囊)和对照组(异烟肼、利福喷丁、乙胺丁醇、左氧氟沙星)，对症状改善情况、药物不良反应、痰涂片浓缩集菌抗酸菌检测、胸部CT结果进行对比分析。结果 ①观察组与对照组的症状改善率分别为85.59%、73.61%(P<0.05)。②观察组与对照组的药物不良反应发生率分别为14.29%、33.33%(P<0.05)。③观察组与对照组3个月末痰涂片阴转率分别为89.29%、74.07%(P<0.05)。④观察组与对照组在治疗3个月末复查胸部CT，病灶有效率分别为75%、55.56%，空洞有效率分别为62.5%、33.33%(P<0.05)。结论 抗痨胶囊与化学药物联合使用具有良好的协同作用，值得临床推广。
【关键词】
抗痨胶囊；结核；老年；初治
Application effects of antiphthisis capsule on elderly patients with new smear positive pulmonary tuberculosis
ZHANG Jie, YANG Xuwen, XU lin, et al. Department of Respiratory Medicine, the Fourth Peoples Hospital of Ningxia,Yinchuan 750021, China
【Abstract】 Objective
To discuss the clinical effects of antiphthisis capsule on elderly patients with new smear positive pulmonary tuberculosis. Methods 110 patients with pulmonary tuberculosis were randomly divided into observe group(isoniazid,rifapentine,ethambutol,levofloxacin,antiphthisis capsule) and control group(isoniazid,rifapentine,ethambutol,levofloxacin)randomly. We observed and analyzed the side effects of antituberculosis drugs, the improvement of clinical symptoms, results of chest CT, sputum examination for antiacid in contrast. Results ① The improvement of clinical symptoms were respectively 85.59%、73.61% (P<0.05) in the observe and the control group. ② The side effect rate was 14.29% in the treatment group and 33.33% in the control group. ③ By the end of 3 months, the sputum smear negative conversion rates were respectively 89.29%,74.07%(P<0.05) in two groups. ④Through examination of chest CT at the third month, effect rates the sputum between two groups respectively were 75%,55.56%, and cavity effective rate were 62.5%,33.33% (P<0.05).Conclusion Antiphthisis capsule combined with chemical medicine on the elderly patients with new smear positive pulmonary tuberculosis is effective and safe, there is a synergistic effect, and it is worthily recommended in the clinical application.
【Key words】
Antiphthisis capsule；Tuberculosis；The elderly；Initial treatment ......
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