幽门螺杆菌感染对2型糖尿病患者糖脂代谢的影响(1)
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【摘要】 目的 探讨幽门螺杆菌(Helicobacter pylori，H.pylori)感染对2型糖尿病(T2 dM)患者糖、脂代谢的影响。方法 选择2型糖尿病患者68例为研究对象，检测空腹血糖、血脂、H.pylori等指标。按H.pylori感染检查结果分为两组：H.pylori阳性DM组(DM1组)，H.pylori阴性DM组(DM2组)；比较两组患者血糖、血脂的差异。结果 ①空腹血糖水平： DM1组比DM2组高，差异有统计学意义(P<0.05)。②血脂水平： DM1组TC、TG比DM2组高，DM1组HDL，C比DM2组低，DM1组与DM2组LDL，C差异无统计学意义。③ H.pylori感染与代谢综合征患者外周炎症反应标志物(CRP、Fg、PLT、WBC)的相关性：其中MS 1组Fg (4.51±0.87)g/L比MS 2组(4.13±0.72)g/L高，两者比较差异有统计学意义(P<0.05)。结论 合并H.pylori感染的DM患者血糖不易被控制。H.pylori感染能够使DM患者的TC、TG水平升高，HDL，C水平降低。但对LDL，C无影响。
【关键词】幽门螺杆菌;2型糖尿病;血糖;血脂
Helicobacter pylori infection and related risk factors in type 2 diabetes research WEI Ai，feng.
Department of Preventive Medicine,The People’s Hospital of Weifang 261041,China
【Abstract】 Objective To explore the Helicobacter pylori (Helicobacter pylori, H.pylori) infection and type 2 diabetes mellitus (T2 dM) the relationship between a variety of factors, observed in patients with T2 dM H.pylori infection on glucose and lipid metabolism.Methods Diagnosis and exclusion criteria, select the endocrine outpatients of T2 dM 68 patients (T2 dM group), 36 cases of males and 32 females, age (50±11.2)years; All subjects were detected H.pylori blood glucose, blood lipids, and body height, weight, waist and hip circumferences measured, respectively, body mass index (BMI), waist to hip ratio (WHR) by H.pylori infection screening were divided into: ① H.pylori，positive T2 dM group (DM1 group) ② H.pylori negative T2 dM group (DM2 group). Results ① Fasting glucose levels of DM1 group was higher than in DM2, there were differences (P<0.05). ② H.pylori infection in patients with diabetes, the relationship between serum lipid levels of DM1 group TC, TG higher, and HDL，C lower than the DM2 group, there were differences (P<0.05). Conclusion H.pylori infection can make glucose and lipid metabolism disorder more seriously in patients with T2 dM.
【Key words】Type 2 diabetes; Helicobacter pylori; Blood glucose;Blood fat
自1982年Warren和Marshsall首次从胃炎和消化性溃疡患者胃窦部分离出来H ......
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