银杏叶提取物联合SSRIs对老年冠心病患者合并抑郁的疗效分析
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【摘要】 目的 探讨银杏叶提取物(Extract of Ginkgo Biloba,EGb)联合常规抗抑郁治疗老年冠心病(CAD)伴抑郁症(depression)的效果。方法 老年冠心病伴抑郁患者分别进入西肽普兰单药治疗组及银杏叶联合西肽普兰提取物治疗组,并对冠心病症状、心电图及抑郁量表进行评价。结果 两组患者冠心病、抑郁症状均明显改善,银杏叶提取物联合治疗组症状的改善更加明显。结论 老年冠心病伴抑郁症患者抗抑郁治疗效果较好,银杏叶提取物对老年冠心病伴抑郁症有良好治疗效果。
【关键词】 老年抑郁;冠心病;银杏叶提取物;SSRIs
The study of late life coronary attery disease with depressive symptom by Egb and SSRIS MA Yongsheng. Department of Senile Disease of Weifang People Hospital,Weifang 261041,China
【Abstract】 Objective To discuss the effect of Egb pluss routine antidepresant for latelife CAD with depressive symptom. Methods All of latelife CAD patients were divided into SSRIs group and Egb pluss SSRIs group, CAD symptome ECG and depression scale was measured to different therapy stage. Results The CAD and depress symptoms in the both two groups were improved obviously.The clinical effect in association group was better than solitary group.Conclusion The therapeutic efficacy to latelife CAD with depressive symptom was good and Egb has better therapeutic efficacy to latelife CAD with depression.
【Key words】 Late life depression;Coronary attery disease Egb; SSRIs
抑郁障碍是冠心病常见的心理障碍之一,心理障碍的存在不仅影响患者的生存质量,也是冠心病的一个危险因素[1]。因此对此类患者需要抗抑郁与心血管病同治。本研究
作者单位:261041 山东省潍坊市人民医院老年病科
旨在探讨银杏叶提取物联合西肽普兰治疗老年冠心病伴抑郁症的临床疗效及副反应。
1 资料与方法
1.1 一般资料 收集2009年7月至2012年3月潍坊市人民医院老年病科病房的老年冠心病住院患者,依据美国精神
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