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老年急性心肌梗死经皮冠状动脉介入治疗的临床研究(1)
http://www.100md.com 2016年12月25日 《中国实用医药》 2016年第36期
     【摘要】 目的 研究分析老年急性心肌梗死患者经皮冠状动脉介入治疗(PCI)的临床效果。方法 急性心肌梗死老年患者224例, 随机分为对照组和观察组, 各112例。对照组患者采用溶栓治疗, 观察组患者应用经皮冠状动脉介入治疗, 观察对比两组患者临床效果。结果 治疗后, 对照组患者中显效43例, 有效47例, 无效22例;观察组患者中显效63例, 有效42例, 无效7例;对照组治疗总有效率为80.4%, 低于观察组的93.8%, 比较差异具有统计学意义(P<0.05)。治療期间, 观察组患者的不良反应发生率为6.3%, 其中1例过敏、3例出血、3例室性心律失常;对照组患者的不良反应发生率为17.9%, 其中过敏5例、出血6例, 室性心律失常9例;观察组不良反应发生率低于对照组, 差异具有统计学意义(P<0.05)。结论 在老年急性心肌梗死患者的治疗中, 相对于常规的静脉溶栓治疗措施, 患者经皮冠状动脉介入治疗临床效果更显著, 且还可减少治疗期间不良反应的产生, 具有推广价值。

    【关键词】 急性心肌梗死;经皮冠状动脉介入治疗;分析;老年

    DOI:10.14163/j.cnki.11-5547/r.2016.36.067

    【Abstract】 Objective To research and analyze clinical effect by percutaneous coronary intervention (PCI) for senile acute myocardial infarction patients. Methods A total of 224 senile acute myocardial infarction patients were randomly divided into control group and observation group, with 112 cases in each group. The control group received thrombolytic therapy, and the observation group received percutaneous coronary intervention for treatment. Clinical effects were observed and compared between the two groups. Results After treatment, the control group had 43 excellent cases, 47 effective cases and 22 ineffective cases. There were 63 excellent cases, 42 effective cases and 7 ineffective cases in the observation group. The control group had lower total effective rate as 80.4% than 93.8% in the observation group, and the difference had statistical significance (P<0.05). During treatment, the observation group had incidence of adverse reactions as 6.3%, along with 1 case with allergy, 3 cases with hemorrhage and 3 cases with ventricular arrhythmias. The control group had incidence of adverse reactions as 17.9%, with 5 cases with allergy, 6 cases with hemorrhage and 9 cases with ventricular arrhythmias. The observation group had lower incidence of adverse reactions than the control group, and the difference had statistical significance (P<0.05). Conclusion Comparing with conventional intravenous thrombolytic therapy in treating senile acute myocardial infarction patients, percutaneous coronary intervention provides more precisely clinical effect, along with reduced adverse reactions during treatment. This method contains promoting value.

    【Key words】 Acute myocardial infarction; Percutaneous coronary intervention; Analyze; Senile

    急性心肌梗死好发于老年人, 是临床中一种常见的疾病, 病情发展迅速, 死亡率较高。该种疾病产生主要是冠状动脉粥样硬化斑块损伤内皮, 产生继发性血栓与斑块破裂, 以此造成冠状动脉急性闭塞, 最后引起心肌坏死[1-4]。针对此种疾病的危险性, 如何有效治疗预防梗死面积扩大, 是当前临床研究的重点内容。本文研究分析老年急性心肌梗死经皮冠状动脉介入治疗的临床效果, 现报告如下。, 百拇医药(徐艳慧)
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