彩超引导下细针穿刺诊断甲状腺结节的应用价值(1)
【摘要】 目的 研究彩超引導下细针穿刺活检(US-FNAB)在甲状腺结节诊断中的临床价值。方法 在彩超引导下对41例甲状腺结节(直径0.5～1.5 cm)患者行US-FNAB， 分析检查结果， 与术后病理进行对比， 从而判断US-FNAB的准确率。结果 患者手术后病理结果：甲状腺良性结节7例(结节性甲状腺肿 3例， 桥本氏甲状腺炎1例， 腺瘤3例)， 其中US-FNAB 诊断良性病变 5例， 无法判断病理类型1例， 取材过少无法诊断1例。甲状腺癌 34例(乳头状癌 32例， 髓样癌 1例， 滤泡性癌1例)， 其中US-FNAB诊断恶性结节32例， 无法判断病理类型1例， 取材过少无法诊断1例。US-FNAB诊断甲状腺结节准确性、敏感性分别为90.2%和95.1%。US-FNAB细胞学结果与手术病理的一致性Kappa=0.694， χ2检验P=0.480>0.05， 提示 US-FNAB与手术病理结果诊断的一致性良好。41例行 US-FNAB穿刺的患者均未发生出血、声音嘶哑、吞咽和呼吸困难等明显并发症。结论 US-FNAB应用于甲状腺结节的诊断准确率高， 且具有操作快速、安全的特点， 是诊断甲状腺结节安全有效的方法。
【关键词】 甲状腺结节；彩超；细针穿刺活检
DOI：10.14163/j.cnki.11-5547/r.2017.07.019
Application value of color Doppler ultrasound-guided fine needle aspiration biopsy in diagnosis of thyroid nodule WANG Feng-yun， SUN Huai-yu， ZHANG Hui-juan. Department of Ultrasonography， First Affiliated Hospital of Baotou Medical College of Inner Mongolia University of Science and Technology， Baotou 014010， China
【Abstract】 Objective To research clinical value of color Doppler ultrasound-guided fine needle aspiration biopsy (US-FNAB) in diagnosis of thyroid nodule. Methods US-FNAB was applied in 41 thyroid nodule cases (diameter 0.5～1.5 cm) under guidance by color Doppler ultrasound， and test outcomes were analyzed. Comparison was made on the outcomes and postoperative pathological outcome to evaluate accuracy of US-FNAB. Results Postoperative pathological outcome in patients showed 7 cases with benign thyroid nodule (3 cases with nodular goiter， 1 case with Hashimoto's thyroiditis and 3 cases with adenoma)， including 5 benign cases diagnosed by US-FNAB， 1 case with undeterminable pathological pattern and 1 undiagnosed case due to insufficient sampling. There were 34 cases with thyroid cancer (32 cases with papillary carcinoma， 1 case with medullary carcinoma and 1 case with follicular carcinoma)， including 32 cases with malignant nodule diagnosed by US-FNAB， 1 case with undeterminable pathological pattern and 1 undiagnosed case due to insufficient sampling. In diagnosis of thyroid nodule， US-FNAB showed accuracy and sensitivity respectively as 90.2% and 95.1%. US-FNAB cytological outcome and surgical pathological outcome had consistency Kappa as 0.694 and P in χ2 test as 0.480>0.05， and US-FNAB and surgical pathological outcome had good diagnostic consistency. There were no obvious complications of hemorrhage， hoarseness， dysphagia and dyspnea in 41 cases. Conclusion Application of US-FNAB shows high accuracy in diagnosis of thyroid nodule. Containing advantages of quick operation and safety， it is a safe and effective method in diagnosis of thyroid nodule., 百拇医药(王凤云 孙怀玉 张慧娟)
【关键词】 甲状腺结节；彩超；细针穿刺活检
DOI：10.14163/j.cnki.11-5547/r.2017.07.019
Application value of color Doppler ultrasound-guided fine needle aspiration biopsy in diagnosis of thyroid nodule WANG Feng-yun， SUN Huai-yu， ZHANG Hui-juan. Department of Ultrasonography， First Affiliated Hospital of Baotou Medical College of Inner Mongolia University of Science and Technology， Baotou 014010， China
【Abstract】 Objective To research clinical value of color Doppler ultrasound-guided fine needle aspiration biopsy (US-FNAB) in diagnosis of thyroid nodule. Methods US-FNAB was applied in 41 thyroid nodule cases (diameter 0.5～1.5 cm) under guidance by color Doppler ultrasound， and test outcomes were analyzed. Comparison was made on the outcomes and postoperative pathological outcome to evaluate accuracy of US-FNAB. Results Postoperative pathological outcome in patients showed 7 cases with benign thyroid nodule (3 cases with nodular goiter， 1 case with Hashimoto's thyroiditis and 3 cases with adenoma)， including 5 benign cases diagnosed by US-FNAB， 1 case with undeterminable pathological pattern and 1 undiagnosed case due to insufficient sampling. There were 34 cases with thyroid cancer (32 cases with papillary carcinoma， 1 case with medullary carcinoma and 1 case with follicular carcinoma)， including 32 cases with malignant nodule diagnosed by US-FNAB， 1 case with undeterminable pathological pattern and 1 undiagnosed case due to insufficient sampling. In diagnosis of thyroid nodule， US-FNAB showed accuracy and sensitivity respectively as 90.2% and 95.1%. US-FNAB cytological outcome and surgical pathological outcome had consistency Kappa as 0.694 and P in χ2 test as 0.480>0.05， and US-FNAB and surgical pathological outcome had good diagnostic consistency. There were no obvious complications of hemorrhage， hoarseness， dysphagia and dyspnea in 41 cases. Conclusion Application of US-FNAB shows high accuracy in diagnosis of thyroid nodule. Containing advantages of quick operation and safety， it is a safe and effective method in diagnosis of thyroid nodule., 百拇医药(王凤云 孙怀玉 张慧娟)