3 months of treatment (P<0.05). After 3 months of treatment， there were 40 cases with symptoms of glucocorticoid， and 6-month administration of mifepristone in those patients showed no obvious exacerbation in the existed symptoms. Serum cortisol in the 40 cases with symptoms of glucocorticoid was obviously higher after 3 months of treatment than that before treatment， and it was much lower after 6 months of treatment than that before treatment (P<0.05). All patients had obviously improved clinical symptoms after treatment ......