【摘要】 目的 探讨老年休克性肺炎患者早期全血氨基末端脑钠肽前体(NT-proBNP)水平的临床意义。方法 19例老年休克性肺炎患者， 根据患者治疗10 d后的转归情况分为好转组(8例)和恶化组(11例)。分析两组患者早期NT-proBNP水平。结果 两组患者平均年龄、入科24 h的急性生理功能和慢性健康状况评分系统Ⅱ(APACHE Ⅱ)评分比较， 差异无统计学意义(t=1.390、1.312， P>0.05)。两组患者治疗初始时血浆NT-proBNP水平比较， 差异具有统计学意义(P<0.05)。结论 检测老年休克性肺炎患者治疗初始全血NT-proBNP水平对短期疗效的判断有一定临床意义， 值得临床重视。

    【关键词】 休克性肺炎；感染性休克；氨基末端脑钠肽前体

    DOI：10.14163/j.cnki.11-5547/r.2017.29.005

    【Abstract】 Objective To investigate the clinical significance of early whole blood N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in elderly patients with shock pneumonia. Methods A total of 19 elderly patients with shock pneumonia were divided by outcomes after 10 d of treatment into improvement group (8 cases) and deterioration group (11 cases). Early NT-proBNP levels in two groups was analyzed. Results Both groups had no statistically significant difference in mean age ......