阿司匹林联合氯吡格雷治疗心肌梗死对患者病死率的影响分析(1)
【摘要】 目的 分析阿司匹林聯合氯吡格雷治疗心肌梗死(MI)对患者病死率的影响。方法 84例心肌梗死患者， 随机分为对照组和分析组， 各42例。两组患者均采用常规治疗。对照组给予单一阿司匹林治疗， 分析组给予阿司匹林联合氯吡格雷治疗。比较两组患者的治疗效果、血管再通、血管再阻塞以及死亡情况。结果 治疗后， 分析组显效24例， 显效率为57.14%；好转15例， 好转率为35.71%；无效3例， 无效率为7.14%；总有效39例， 总有效率为92.86%；对照组显效18例， 显效率为42.86%；好转13例， 好转率为30.95%；无效11例， 无效率为26.91%；总有效31例， 总有效率为73.81%；分析组总有效率高于对照组， 差异有统计学意义(P<0.05)。两组血管再通率比较， 差异无统计学意义(P>0.05)。分析组血管再阻塞率低于对照组， 差异有统计学意义(P<0.05)。分析组死亡7例， 死亡率为16.67%；对照组死亡16例， 死亡率为38.10%；分析组死亡率低于对照组， 差异有统计学意义(P<0.05)。结论 心肌梗死患者采用阿司匹林联合氯吡格雷治疗的临床疗效优于单一阿司匹林治疗效果， 还可降低患者死亡率， 有较高临床运用价值。
【关键词】 阿司匹林；氯吡格雷；心肌梗死；病死率
DOI：10.14163/j.cnki.11-5547/r.2017.30.060
Analysis of effect of aspirin combined with clopidogrel on the mortality of patients with myocardial infarction PAN Guang-chu， CHEN Wu， ZHENG Zhi-min. Guandong Province Leizhou City Longmen Town Nongken Second Hospital， Leizhou 524200， China
【Abstract】 Objective To analyze the effect of aspirin combined with clopidogrel on the mortality of patients with myocardial infarction (MI). Methods A total of 84 patients with myocardial infarction were randomly divided into control group and analysis group， with 42 cases in each group. Both groups received conventional therapy， and the control group was treated with aspirin only. The analysis group was treated with aspirin and clopidogrel. Comparison were made on treatment effect， recanalization， vascular re-obstruction， and death conditions between two groups. Results After treatment， the analysis group had 24 excellent cases， accounting for 57.14%， 15 effective cases， accounting for 35.71%， 3 ineffective cases， accounting for 7.14%， with 39 total effective cases， accounting for 92.86%. The control group had 18 excellent cases， accounting for 42.86%，13 effective cases， accounting for 30.95%， 11 ineffective cases， accounting for 26.91%， with 31 total effective cases， accounting for 73.81%. The analysis group had higher total effective rate than the control group， and the difference was statistically significant (P<0.05). Both groups had no statistically significant difference in recanalization rate (p>0.05). The analysis group had lower vascular re-obstruction rate than the control group， and the difference was statistically significant (P<0.05). The analysis group had 7 death cases， accounting for 16.67%， while the control group had 16 death cases， accounting for 38.10%. The analysis group had lower death rate than the control group， and the difference was statistically significant(P<0.05). Conclusion The clinical efficacy of aspirin combined with clopidogrel therapy in patients with myocardial infarction is better than that of single aspirin treatment. It can also reduce the mortality of patients with high clinical application value., http://www.100md.com(潘光楚 陈武 郑志敏)
【关键词】 阿司匹林；氯吡格雷；心肌梗死；病死率
DOI：10.14163/j.cnki.11-5547/r.2017.30.060
Analysis of effect of aspirin combined with clopidogrel on the mortality of patients with myocardial infarction PAN Guang-chu， CHEN Wu， ZHENG Zhi-min. Guandong Province Leizhou City Longmen Town Nongken Second Hospital， Leizhou 524200， China
【Abstract】 Objective To analyze the effect of aspirin combined with clopidogrel on the mortality of patients with myocardial infarction (MI). Methods A total of 84 patients with myocardial infarction were randomly divided into control group and analysis group， with 42 cases in each group. Both groups received conventional therapy， and the control group was treated with aspirin only. The analysis group was treated with aspirin and clopidogrel. Comparison were made on treatment effect， recanalization， vascular re-obstruction， and death conditions between two groups. Results After treatment， the analysis group had 24 excellent cases， accounting for 57.14%， 15 effective cases， accounting for 35.71%， 3 ineffective cases， accounting for 7.14%， with 39 total effective cases， accounting for 92.86%. The control group had 18 excellent cases， accounting for 42.86%，13 effective cases， accounting for 30.95%， 11 ineffective cases， accounting for 26.91%， with 31 total effective cases， accounting for 73.81%. The analysis group had higher total effective rate than the control group， and the difference was statistically significant (P<0.05). Both groups had no statistically significant difference in recanalization rate (p>0.05). The analysis group had lower vascular re-obstruction rate than the control group， and the difference was statistically significant (P<0.05). The analysis group had 7 death cases， accounting for 16.67%， while the control group had 16 death cases， accounting for 38.10%. The analysis group had lower death rate than the control group， and the difference was statistically significant(P<0.05). Conclusion The clinical efficacy of aspirin combined with clopidogrel therapy in patients with myocardial infarction is better than that of single aspirin treatment. It can also reduce the mortality of patients with high clinical application value., http://www.100md.com(潘光楚 陈武 郑志敏)