超微血管成像技术检测颈动脉斑块内新生血管预测脑梗死发生的价值(1)
【摘要】 目的 探讨超微血管成像(SMI)技术检测颈动脉斑块内新生血管预测脑梗死发生的诊断价值。方法 150例颈动脉斑块患者, 均使用SMI技术进行检测, 根据斑块内新生血管分布进行SMI分级, 与CT结果比较(证实有无脑梗死), 分析颈动脉斑块SMI分级与脑梗死发病率之间的关系。结果 150例入选者斑块SMI分级:0级17例, CT证实有脑梗死者8例, 无脑梗死者9例;Ⅰ级40例, CT证实有脑梗死者24例, 无脑梗死者16例;Ⅱ级93例, CT证实有脑梗死者92例, 无脑梗死者1例。随着SMI分级的增加, CT阳性检出率呈上升趋势, 差异具有统计学意义(P<0.01)。SMI分级与CT的相关性分析结果显示, SMI分级与CT结果呈正相关(r=0.516, P<0.01)。结论 利用SMI技术对斑块内新生血管进行检测分析, 可预测脑梗死的发生风险。
【关键词】 超微血管成像;颈动脉斑块;新生血管;脑梗死
DOI:10.14163/j.cnki.11-5547/r.2019.03.009
【Abstract】 Objective To discuss the diagnostic value of superb microvascular imaging (SMI) technique in detecting neovascularization in carotid plaque in predicting cerebral infarction. Methods A total of 150 cases of carotid plaque patients were detected by SMI technique. According to the distribution of neovascularization in the plaque, SMI grading was performed and compared with CT results (confirming the presence of cerebral infarction). The relationship between SMI grading of carotid plaque and the incidence of cerebral infarction was analyzed. Results SMI grade of 150 plaques: 17 cases of grade 0, including 8 cases of cerebral infarction confirmed by CT and 9 cases of non-cerebral infarction; 40 cases of grade I, including 24 cases of cerebral infarction confirmed by CT, 16 cases of non-cerebral infarction; 93 cases of grade II, including 92 cases of cerebral infarction confirmed by CT and 1 case of non-cerebral infarction. With the increase of SMI grade, the positive detection rate of CT showed an upward trend, and the difference was statistically significant (P<0.01). Correlation analysis between SMI grade and CT showed that SMI grade was positively correlated with CT results (r=0.516, P<0.01). Conclusion Detection and analysis of neovascularization in plaque by SMI technique can predict the risk of cerebral infarction.
【Key words】 Superb microvascular imaging; Carotid plaque; Neovascularization; Cerebral infarction
頸动脉粥样硬化斑块的稳定性已成为脑梗死发生与发展的重要因素, 对颈动脉斑块稳定性的评估具有重大意义。近年来研究显示, 对脑梗死发生起决定作用的是不稳定的粥样硬化斑块, 而非斑块致管腔狭窄[1], 导致斑块不稳定的原因除纤维帽的厚薄及完整性、脂质核心的大小、炎症反应程度等因素外, 另一主要因素就是斑块的新生血管情况[2]。本研究利用SMI技术对颈动脉斑块内新生血管进行检测分级, 并与CT结果进行对比, 研究两种的相关性, 为评价斑块的稳定情况提供更加可靠的信息。现报告如下。
1 资料与方法
1. 1 一般资料 选择2017年1月~2018年3月在本院就诊的颈动脉斑块患者150例, 单发55例, 多发95例(多发者选取其中最大者)。男96例, 女54例, 年龄45~76岁, 平均年龄56岁。CT确诊同侧脑梗死124例, 脑梗死发病时间1~10年, 无脑梗死者26例。
1. 2 仪器与方法 选用TOSHIBA Aplio400彩色多普勒超声仪, 探头频率4~9 MHz, 具有SMI技术功能。患者先行颈动脉彩色多普勒超声检查, 观察斑块形态, 大小, 位置, 数目, 回声。然后启动SMI模式, 检测斑块内部有无SMI血流信号。, http://www.100md.com(莎日图 刘婧 王丽娜)
【关键词】 超微血管成像;颈动脉斑块;新生血管;脑梗死
DOI:10.14163/j.cnki.11-5547/r.2019.03.009
【Abstract】 Objective To discuss the diagnostic value of superb microvascular imaging (SMI) technique in detecting neovascularization in carotid plaque in predicting cerebral infarction. Methods A total of 150 cases of carotid plaque patients were detected by SMI technique. According to the distribution of neovascularization in the plaque, SMI grading was performed and compared with CT results (confirming the presence of cerebral infarction). The relationship between SMI grading of carotid plaque and the incidence of cerebral infarction was analyzed. Results SMI grade of 150 plaques: 17 cases of grade 0, including 8 cases of cerebral infarction confirmed by CT and 9 cases of non-cerebral infarction; 40 cases of grade I, including 24 cases of cerebral infarction confirmed by CT, 16 cases of non-cerebral infarction; 93 cases of grade II, including 92 cases of cerebral infarction confirmed by CT and 1 case of non-cerebral infarction. With the increase of SMI grade, the positive detection rate of CT showed an upward trend, and the difference was statistically significant (P<0.01). Correlation analysis between SMI grade and CT showed that SMI grade was positively correlated with CT results (r=0.516, P<0.01). Conclusion Detection and analysis of neovascularization in plaque by SMI technique can predict the risk of cerebral infarction.
【Key words】 Superb microvascular imaging; Carotid plaque; Neovascularization; Cerebral infarction
頸动脉粥样硬化斑块的稳定性已成为脑梗死发生与发展的重要因素, 对颈动脉斑块稳定性的评估具有重大意义。近年来研究显示, 对脑梗死发生起决定作用的是不稳定的粥样硬化斑块, 而非斑块致管腔狭窄[1], 导致斑块不稳定的原因除纤维帽的厚薄及完整性、脂质核心的大小、炎症反应程度等因素外, 另一主要因素就是斑块的新生血管情况[2]。本研究利用SMI技术对颈动脉斑块内新生血管进行检测分级, 并与CT结果进行对比, 研究两种的相关性, 为评价斑块的稳定情况提供更加可靠的信息。现报告如下。
1 资料与方法
1. 1 一般资料 选择2017年1月~2018年3月在本院就诊的颈动脉斑块患者150例, 单发55例, 多发95例(多发者选取其中最大者)。男96例, 女54例, 年龄45~76岁, 平均年龄56岁。CT确诊同侧脑梗死124例, 脑梗死发病时间1~10年, 无脑梗死者26例。
1. 2 仪器与方法 选用TOSHIBA Aplio400彩色多普勒超声仪, 探头频率4~9 MHz, 具有SMI技术功能。患者先行颈动脉彩色多普勒超声检查, 观察斑块形态, 大小, 位置, 数目, 回声。然后启动SMI模式, 检测斑块内部有无SMI血流信号。, http://www.100md.com(莎日图 刘婧 王丽娜)