右美托咪定复合舒芬太尼在腹腔镜下 子宫全切术后静脉自控镇痛中的应用(3)
②右美托咪定抑制交感神經张力, 降低儿茶酚胺的释放, 从而降低血管收缩阈值[7]。本研究结果显示, 试验组总不良反应发生率为33.3%, 低于对照组的66.7%, 差异具有统计学意义(P<0.05)。
综上所述, 右美托咪定复合舒芬太尼用于术后静脉自控镇痛效果确切, 镇静程度适度, 且恶心、呕吐和寒战等不良反应发生较少, 是一种更加优化的镇痛方案。
参考文献
[1] 侯哲, 马红双, 郭瑞, 等. 舒芬太尼联合右美托咪定在骨科围手术期ICU机械通气患者中的应用. 医药论坛杂志, 2016, 37(1):143-144.
[2] 韩阳东, 陈鹏, 赵加, 等. 盐酸右美托咪定配合舒芬太尼镇痛泵对老年髋关节置换病人术后镇痛及髋关节功能康复的影响. 中国实验诊断学, 2014(8):1354-1355.
[3] Carollo DS, Nossaman BD, Ramadhyani U. Dexmedetomidine: A review of clinical applications. Current opinion in anaesthesiology, 2008, 21(4):457-461.
[4] Afonso J, Reis F. Dexmedetomide: current role in anesthesia and intensive care. Rev Bras Anestesiol, 2012, 62(1):118-133.
[5] Zaben KRA. A balanced anesthesia with dexmedetomidine decreases postoperative nausea and vomiting after laparoscopic surgery. Saudi medical journal, 2009, 30(12):1537-1541.
[6] Everett LL, Rooyen IFV, Warner MH, et al. Use of dexmedetomidine in awake craniotomy in adolescents: Report of two cases. Pediatric Anesthesia, 2006, 16(3):338-342.
[7] Weant KA, Martin JE, Humphries RL, et al. Pharmacologic options for reducing the shivering response to therapeutic hypothermia. Pharmacotherapy the Journal of Human Pharmacology & Drug Therapy, 2012, 30(8):830-841.
[收稿日期:2018-12-24], 百拇医药(郭迎霞 袁爱武 刘威)
综上所述, 右美托咪定复合舒芬太尼用于术后静脉自控镇痛效果确切, 镇静程度适度, 且恶心、呕吐和寒战等不良反应发生较少, 是一种更加优化的镇痛方案。
参考文献
[1] 侯哲, 马红双, 郭瑞, 等. 舒芬太尼联合右美托咪定在骨科围手术期ICU机械通气患者中的应用. 医药论坛杂志, 2016, 37(1):143-144.
[2] 韩阳东, 陈鹏, 赵加, 等. 盐酸右美托咪定配合舒芬太尼镇痛泵对老年髋关节置换病人术后镇痛及髋关节功能康复的影响. 中国实验诊断学, 2014(8):1354-1355.
[3] Carollo DS, Nossaman BD, Ramadhyani U. Dexmedetomidine: A review of clinical applications. Current opinion in anaesthesiology, 2008, 21(4):457-461.
[4] Afonso J, Reis F. Dexmedetomide: current role in anesthesia and intensive care. Rev Bras Anestesiol, 2012, 62(1):118-133.
[5] Zaben KRA. A balanced anesthesia with dexmedetomidine decreases postoperative nausea and vomiting after laparoscopic surgery. Saudi medical journal, 2009, 30(12):1537-1541.
[6] Everett LL, Rooyen IFV, Warner MH, et al. Use of dexmedetomidine in awake craniotomy in adolescents: Report of two cases. Pediatric Anesthesia, 2006, 16(3):338-342.
[7] Weant KA, Martin JE, Humphries RL, et al. Pharmacologic options for reducing the shivering response to therapeutic hypothermia. Pharmacotherapy the Journal of Human Pharmacology & Drug Therapy, 2012, 30(8):830-841.
[收稿日期:2018-12-24], 百拇医药(郭迎霞 袁爱武 刘威)