腹腔镜下卵巢子宫内膜异位囊肿改良剔除术对卵巢功能的影响研究(1)
【摘要】 目的 觀察分析腹腔镜下卵巢子宫内膜异位囊肿改良剔除术对卵巢功能的影响。方法 120例卵巢子宫内膜异位囊肿患者， 按照治疗方法不同分为实验组和对照组， 每组60例。实验组应用腹腔镜下卵巢子宫内膜异位囊肿改良剔除术， 术中局部应用稀释注射垂体后叶素(生理盐水20～60 ml+垂体后叶素6～12单位)、锐性剥离方法;对照组应用腹腔镜手术但是未使用垂体后叶素及钝性撕拉法。比较两组患者的手术时间、术中出血量、术后体温、肛门排气时间以及手术前后血红蛋白、糖类抗原125(CA125)、卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)水平及窦状卵泡数。结果 手术前， 两组患者血红蛋白、CA125、FSH、LH、E2水平及窦状卵泡数比较差异无统计学意义(P>0.05);手术后， 实验组患者血红蛋白、CA125、FSH、LH、E2水平及窦状卵泡数均优于对照组， 差异具有统计学意义(P<0.05)。实验组患者手术时间(106.3±10.8)min、肛门排气时间(18.2±3.5)min短于对照组的(129.9±15.4)min、(22.4±5.4)h， 术中出血量(112.2±30.2)ml少于对照组的(185.5±56.5)ml， 术后体温(36.8±0.3)℃低于对照组的(37.2±0.5)℃， 差异具有统计学意义(P<0.05)。结论 腹腔镜下卵巢子宫内膜异位囊肿改良剔除术能够有效保护其卵巢功能， 缩短患者手术时间、肛门排气时间， 减少术中出血量， 具有重要的临床应用价值。
【关键词】 腹腔镜下;卵巢子宫内膜异位囊肿改良剔除术;卵巢功能
DOI：10.14163/j.cnki.11-5547/r.2020.23.006
【Abstract】 Objective To observe and analyzed the effect of modified laparoscopic cystectomy for ovarian endometriosis cyst on ovarian function. Methods A total of 120 ovarian endometriosis cyst patients were divided into experimental group and control group by different treatment methods， with 60 cases in each group. The experimental group received modified laparoscopic cystectomy for ovarian endometriosis cyst， and the intraoperative local application of dilute injection of hypophysin (physiological saline 20-60 ml + hypophysin 6-12 units)， sharp dissection method. The control group received laparoscopic surgery but not pituitrin and blunt tearing during surgery. The surgery time， amount of intraoperative hemorrhage， postoperative temperature， anal exhaust time， hemoglobin， carbohydrate antigen 125 (CA125)， follicle stimulating hormone (FSH)， luteinizing hormone (LH)， estradiol (E2) levels and number of sinusoidal follicles before and after surgery were compared between the two groups. Results Before surgery， there was no statistically significant difference in hemoglobin， CA125， FSH， LH， E2 levels and number of sinusoidal follicles between the two groups (P>0.05). After surgery， hemoglobin， CA125， FSH， LH， E2 levels and number of sinusoidal follicles of the experimental group were better than those of the control group， and the difference was statistically significant (P<0.05). The surgery time (106.3±10.8) min， anal exhaust time (18.2±3.5) min of the experimental group were shorter than those of the control group (129.9±15.4) min， (22.4±5.4) h， amount of intraoperative hemorrhage (112.2±30.2) ml was less than that of the control group (185.5±56.5) ml， and postoperative temperature (36.8±0.3)℃ was lower than that of the control group (37.2±0.5)℃. The difference was statistically significant (P<0.05). Conclusion Modified laparoscopic cystectomy for ovarian endometriosis cyst can effectively protect its ovarian function， shorten the surgery time of patients， anal exhaust time， and reduce the amount of intraoperative hemorrhage. It contains great clinical value., http://www.100md.com(宁林莹 陈梽烈)
【关键词】 腹腔镜下;卵巢子宫内膜异位囊肿改良剔除术;卵巢功能
DOI：10.14163/j.cnki.11-5547/r.2020.23.006
【Abstract】 Objective To observe and analyzed the effect of modified laparoscopic cystectomy for ovarian endometriosis cyst on ovarian function. Methods A total of 120 ovarian endometriosis cyst patients were divided into experimental group and control group by different treatment methods， with 60 cases in each group. The experimental group received modified laparoscopic cystectomy for ovarian endometriosis cyst， and the intraoperative local application of dilute injection of hypophysin (physiological saline 20-60 ml + hypophysin 6-12 units)， sharp dissection method. The control group received laparoscopic surgery but not pituitrin and blunt tearing during surgery. The surgery time， amount of intraoperative hemorrhage， postoperative temperature， anal exhaust time， hemoglobin， carbohydrate antigen 125 (CA125)， follicle stimulating hormone (FSH)， luteinizing hormone (LH)， estradiol (E2) levels and number of sinusoidal follicles before and after surgery were compared between the two groups. Results Before surgery， there was no statistically significant difference in hemoglobin， CA125， FSH， LH， E2 levels and number of sinusoidal follicles between the two groups (P>0.05). After surgery， hemoglobin， CA125， FSH， LH， E2 levels and number of sinusoidal follicles of the experimental group were better than those of the control group， and the difference was statistically significant (P<0.05). The surgery time (106.3±10.8) min， anal exhaust time (18.2±3.5) min of the experimental group were shorter than those of the control group (129.9±15.4) min， (22.4±5.4) h， amount of intraoperative hemorrhage (112.2±30.2) ml was less than that of the control group (185.5±56.5) ml， and postoperative temperature (36.8±0.3)℃ was lower than that of the control group (37.2±0.5)℃. The difference was statistically significant (P<0.05). Conclusion Modified laparoscopic cystectomy for ovarian endometriosis cyst can effectively protect its ovarian function， shorten the surgery time of patients， anal exhaust time， and reduce the amount of intraoperative hemorrhage. It contains great clinical value., http://www.100md.com(宁林莹 陈梽烈)