DNA甲基化与阿尔茨海默病的发病机制(2)
[4] Grubb MS， Burrone J. Building and maintaining the axon initial segment[J]. Curr Opin Neurobiol ， 2010， 20： 1-8.
[5] Espada J， Ballestar E， Santoro R， et al. Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase1 (Dnmt1) deficient cells[J]. Nucleic Acids Res， 2007， 35： 2191-2198.
[6] Mattson MP. Methylation and acetylation in nervous system development and neurodegenerative disorders[J]. Ageing Res Rev， 2003， 2： 329-342.
[7] Jing-Zhi Guan， Wei-Ping Guan， Toyoki Maeda， et al. The Subtelomere of Short Telomeres is Hypermethylated in Alzheimer’s Disease[J]. Aging and Disease， 2012， 3(2)： 164-170.
[8] Zhou Y， Grummt I. The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing[J]. Curr Biol， 2005， 15： 1434-1438.
[9] Song C X， Szulwach K E， et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine[J]. Nat Biotechnol， 2011， 29： 68-72.
[10] Bihaqi S W， Huang H， et al.Infant exposure to lead(Pb) and epigenetic modifications in the aging primate brain： implications for Alzheimer’s disease[J]. J Alzheimer’s Dis，2011， 27： 819-833., http://www.100md.com(张旭 赵志英)
[5] Espada J， Ballestar E， Santoro R， et al. Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase1 (Dnmt1) deficient cells[J]. Nucleic Acids Res， 2007， 35： 2191-2198.
[6] Mattson MP. Methylation and acetylation in nervous system development and neurodegenerative disorders[J]. Ageing Res Rev， 2003， 2： 329-342.
[7] Jing-Zhi Guan， Wei-Ping Guan， Toyoki Maeda， et al. The Subtelomere of Short Telomeres is Hypermethylated in Alzheimer’s Disease[J]. Aging and Disease， 2012， 3(2)： 164-170.
[8] Zhou Y， Grummt I. The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing[J]. Curr Biol， 2005， 15： 1434-1438.
[9] Song C X， Szulwach K E， et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine[J]. Nat Biotechnol， 2011， 29： 68-72.
[10] Bihaqi S W， Huang H， et al.Infant exposure to lead(Pb) and epigenetic modifications in the aging primate brain： implications for Alzheimer’s disease[J]. J Alzheimer’s Dis，2011， 27： 819-833., http://www.100md.com(张旭 赵志英)