炎琥宁治疗呼吸道合胞病毒肺炎100例疗效观察(1)
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【摘要】 目的 观察炎琥宁治疗呼吸道合胞病毒肺炎的疗效。方法 选择2006年10月至2009年10月本院住院的符合病例纳入标准的呼吸道合胞病毒肺炎200例,随机分入治疗组与对照组各100例,均给予布地奈德雾化、吸氧、补液等常规治疗,治疗组在此基础上加用炎琥宁注射液(10 mg/(kg•d),静滴,1次/d)治疗,共7 d,比较2组疗效。结果 治疗组显效60例,有效34例,无效6例,对照组显效23例,有效50例,无效27例,两组比较疗效差异有统计学意义(χ2=32.91,P<0.01),治疗组和对照组的总有效率分别为94.00%、73.00%,两组比较经卡方检验差异有统计学意义(χ2=16.00,P<0.01)。结论 炎琥宁治疗呼吸道合胞病毒肺炎疗效较好,值得临床使用。
【关键词】炎琥宁;呼吸道合胞病毒; 肺炎
Observation on the efficacy of Andrographolide in 100 cases of respiratory syncytial virus pneumonia
LI Zhi-wen.Department of Paediatrics HuangJiang Hospital,Dongguan,528200,China
【Abstract】 Objective To observe the efficacy of Andrographolide in 100 cases of respiratory syncytial
DOI:10.3760/cma.j.issn 1673-8799.2010.06.51
作者单位:523750广东省东莞市黄江医院儿科
virus pneumonia.Methods 200 cases of respiratory syncytial virus pneumonia according with internalized standard were medially divided into the treatment group and the control group at random,which had been hospitalized from October 2006 to October 2009.They were treated by Budesonide atomization and inhaling oxygen and supplying liquid,etc,while the treatment group was healed by Andrographolide injection(10 mg/(kg•d),intravenous drip,one time a day) with five days additionally,then the efficacy of two groups was contrasted.Results The excellence cases in treatment group were 60 cases,the utility cases were 34 cases,the invalid cases were 6 cases,however,the excellence cases in control group were 23 cases,the utility cases were 50 cases,the invalid cases were 27 cases.The efficacy of two groups was significantly different(χ2=32.91,P<0.01).The total effective rate in treatment group were obviously higher than that in control group(χ2=16.00,P<0.01),which was 94.00%,73.00%respectively.Conclusion The efficacy of Andrographolide in respiratory syncytial virus pneumonia is good;it is worth using in clinic.
【Key words】Andrographolide;Respiratory syncytial virus; Pneumonia
呼吸道合胞病毒(Respiratory syncytial virus,RSV)是引起小儿呼吸道感染最常见的病原体,也是诱发婴幼儿哮喘发作的主要原因[1]。呼吸道合胞病毒肺炎多见于2~6个月婴幼儿,以喘憋为主要表现,严重时并发呼吸衰竭、心力衰竭危及患儿生命[2] ......
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