监测血清TNF-α和IL-6水平在重症急性胰腺炎患者的变化及意义(1)
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[摘要] 目的探讨TNF-α和IL-6在重症急性胰腺炎(SAP)患者血清中的变化及临床意义。方法应用ELISA法检测32例重症急性胰腺炎及25例对照组血清TNF-α、IL-6的水平变化。结果入院时SAP患者TNF-α水平(48.5±12.1)pg/mL显著高于对照组(13.5±3.8)pg/mL,IL-6 水平SAP患者(66.7±19.3)pg/mL较对照组(42.3±14.2)pg/mL无明显升高;SAP患者血清IL-6在入院的第7天升高最明显(180.1±41.4)pg/mL,高于对照组,在入院第14天SAP患者血清TNF-α(29.5±9.5)pg/mL,IL-6 (102.8±24.6)pg/mL仍然高于对照组。结论检测血清TNF-α和IL-6的水平变化,对重症急性胰腺炎的早期诊断、病情判断和预后评估具有重要的应用价值。
[关键词] 重症急性胰腺炎;肿瘤坏死因子-α;白细胞介素-6
[中图分类号] R576 [文献标识码] A[文章编号] 1673-9701(2009)34-04-02
Dynamic Changes and Clinical Significance of Serum TNF-α and IL-6 in Severe Acute Pancreatitis
CHAI HulinWANG DeqiangLIU Tiejun
General Surgery,the First Affiliated Hospital of Baotou Medical College,Baotou 014010,China
[Abstract] ObjectiveTo investigate the changes and clinical significance of serum TNF-α and IL-6 in severe acute pancreatitis(SAP) ......
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