[摘要] 目的 探讨左旋氨氯地平对不稳定型心绞痛(UAP)的临床疗效。方法 采用随机、单盲、对照研究;236例UAP患者随机分为左旋氨氯地平治疗组(118例)和常规治疗组(118例)。左旋氨氯地平治疗组:在常规治疗基础上加用左旋氨氯地平,2.5mg,每日1次,共4周;常规治疗组:消心痛10mg/次,3次/d。结果 左旋氨氯地平治疗组总有效率89.83%和83.90%,显著高于常规治疗组的71.19%和63.56%;无严重不良反应。结论 左旋氨氯地平可以有效地治疗不稳定型心绞痛。

    [关键词] 不稳定型心绞痛;左旋氨氯地平;临床研究

    [中图分类号] R541.4[文献标识码] A [文章编号] 1673-9701(2009)36-147-02

    Levamlodipine for Unstable Angina Pectoris

    WANG Qizhu

    Affiliated Hospital of Shandong Medical College,Linyi 276004,China

    [Abstract] Objective To investigate the clinical efficacy of levamlodipine for the treatment of unstable angina pectoris(UAP). Methods A randomized,single blind,controlled study was carried out in 236 cases of UAP which were randomly divided into levamlodipine treatment group (118 cases) and conventional treatment group(118 cases). Levamlodipine,2.5mg,once a day for 4 weeks was given to the levamlodipine treatment group on the based of conventional therapy. The conventional treatment group was given isosorbide dinitrate 10mg/time,3 times/day. Results The total effective rates in the levamlodipine treatment group were 89.83% and 83.9% with no adverse reactions,significantly higher than those of the conventional treatment group(71.19% and 63.56%). Conclusion Levamlodipine can be used for effective treatment for unstable angina pectoris. ......