妊娠合并甲状腺疾病的围产结局58例临床分析(2)
综上所述,甲状腺功能的异常,即甲状腺功能亢进或减低,都将对围产结局产生影响,而其中主要是妊娠期的甲状腺功能水平,若孕期甲状腺功能正常,则分娩过程不受影响,可娩出正常的新生儿。因此,开展对孕前及孕期母体甲状腺功能监测十分重要。Haddow 等[6]和Fisher[7]均提出妊娠期应经常评价甲状腺功能,估计可能的甲状腺功能异常,并监测以前存在的甲状腺疾病。Mestman[2]建议甲状腺功能测试应在诊断妊娠时及28～32孕周之内进行。加强孕产妇保健,提高对妊娠合并甲状腺疾病的认识和意识,并给予及时恰当的诊断和治疗,以保证正常的围产结局。
[参考文献]
[1] Lazarus JH. Epidemiology and prevention of thyroid disease in pregnancy[J]. Thyroid,2002,12(10):861-865.
[2] Mestman TH. Hyperthyroidism in pregnancy[J]. Clin Obstet Gynecol,1997, 40(1):45-64.
[3] Brown RS. Autoimmune thyroid disease in pregnant women and their offspring[J]. Endocr Pract. 1996,2(1):53-61.
[4] Montoro MN. Management of Hyperthyroidism during pregnancy[J]. Clin Obstet Gynecol,1997,40(1):65-80.
[5] Porterfield SP,Hendrich CE. The role of hormones in prenatal and neonatal neurological development-current perspectives[J]. Endocrine Rev,1993,14(1):94.
[6] Haddow JE,Palomaki GE,Allan WO,et al. Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child[J]. N Engl J Med,1999,341(8):549-555.
[7] Fisher DA. Thyroid function:diagnosis and management of fetal thyroid disordes[J]. Clin Obstet Gynecol,1997,40(1):16-31.
(收稿日期:2009-05-26), http://www.100md.com(莫翠玲 赖 坚)
[参考文献]
[1] Lazarus JH. Epidemiology and prevention of thyroid disease in pregnancy[J]. Thyroid,2002,12(10):861-865.
[2] Mestman TH. Hyperthyroidism in pregnancy[J]. Clin Obstet Gynecol,1997, 40(1):45-64.
[3] Brown RS. Autoimmune thyroid disease in pregnant women and their offspring[J]. Endocr Pract. 1996,2(1):53-61.
[4] Montoro MN. Management of Hyperthyroidism during pregnancy[J]. Clin Obstet Gynecol,1997,40(1):65-80.
[5] Porterfield SP,Hendrich CE. The role of hormones in prenatal and neonatal neurological development-current perspectives[J]. Endocrine Rev,1993,14(1):94.
[6] Haddow JE,Palomaki GE,Allan WO,et al. Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child[J]. N Engl J Med,1999,341(8):549-555.
[7] Fisher DA. Thyroid function:diagnosis and management of fetal thyroid disordes[J]. Clin Obstet Gynecol,1997,40(1):16-31.
(收稿日期:2009-05-26), http://www.100md.com(莫翠玲 赖 坚)