临床研究中骨折愈合过程的评价方法进展(2)
3结论
随着骨科学的发展,尤其是骨折固定方法和固定原则的完善,不同干预因素对骨折愈合过程影响的各不相同,如何得到正确且精确的评价方法已越来越受到骨科界的注意,采用不同治疗方法时由于骨折愈合方式不同,也可能采用不同的测量方法。骨折愈合是多种因素相互协调、相互拮抗作用的结果。单一考虑某一因素而得出最终结论是不可靠的,并且,许多检测指标在临床上的推广有待进一步的研究和改进。一种指标不可能适合于所有骨折愈合过程的评价。
[参考文献]
[1] Whelan DB, Bhandari M, McKee MD, et al. Interobserver and intraobserver variation in the assessment of the healing of tibial fractures after intramedullary fixation[J]. J Bone Joint Surg Br,2002, 84:15-18.
, http://www.100md.com
[2] Szechinski JW,Grigorian MA,Grainger AJ,et al. Femoral neck and intertrochanteric fractures:radiographic indicators of fracture healing[J]. Orthopedics,2002,25:1365-1368.
[3] Cattermole HC,Fordham JN,Muckle DS,et al. Dual-energy X-ray absorptiometry as a measure of healing in fractures treated by intramedullary nailing[J]. J Orthop Trauma,1996,10:563-568.
[4] Smith MA,Jones EA,Strachan RK,et al. Prediction of fracture healing in the tibia by quantitative radionuclide imaging[J]. J Bone Joint Surg Br,1987,69:441-447.
, 百拇医药
[5] Wallace AL,Strachan RK,Blane A,et al. Quantitative early phase scintigraphy in the prediction of healing of tibial fractures[J]. Skeletal Radiol,1992,21:241-245.
[6] Bossy E,Talmant M,Peyrin F,et al. An in vitro study of the ultrasonic axial transmission technique at the radius: 1-MHz velocity measurements are sensitive to both mineralization and intracortical porosity[J]. J Bone Miner Res,2004,19(9):1548-1556.
[7] Lefebvre F,Deblock Y,Campistron P,et al. Development of a new ultrasonic technique for bone and biomaterials in vitro character- ization[J]. J Biomed Mater Res,2002,63(4):441-446.
, http://www.100md.com
[8] Malizos KN,Papachristos AA,Protopappas VC,et al. Transosseous application of low-intensity ultrasound for the enhancement and monitoring of fracture healing process in a sheep osteotomy model[J]. Bone,2006,38: 530-539.
[9] Protopappas VC,Baga DA,Fotiadis DI,et al. An ultrasound wearable system for the monitoring and acceleration of fracture healing in long bones[J]. IEEE Trans Biomed Eng,2005,52(9):1597-1608.
[10] Grigoryan M, Lynch JA, Fierlinger AL, et al. Quantitative and qualitative assessment of closed fracture healing using computed tomography and conventional radiography[J]. Acad Radiol,2003,10:1267-1273.
, 百拇医药
[11] Bhattacharyya T,Bouchard KA,Phadke A,et al. The accuracy of computed tomography for the diagnosis of tibial nonunion[J]. J Bone Joint Surg Am,2006,88:692-697.
[12] Den Boer FC,Bramer JA,Patka P,et al. Quantification of fracture healing with three-dimensional computed tomography[J]. Arch Orthop Trauma Surg,1998,117:345-350.
[13] Lowet G,Dayuan X,Van der Perre G. Study of the vibrational behaviour of ahealing tibia using finite element modelling[J]. J Biomech,1996,29:1003-1010.
, http://www.100md.com
[14] Glinkowski W,Górecki A. Clinical experiences with ultrasonometric measurement of fracture healing[J]. Technol Health Care,2006,14:321-333.
[15] Fellinger M,Leitgeb N,Szyszkowitz R,et al. Early detection of delayed union in lower leg fractures using a computerised analysis of mechanical vibration reactions of bone for assessing the state of fracture healing[J]. Arch Orthop Trauma Surg,1994,113:93-96.
[16] Moorcroft CI,Ogrodnik PJ,Thomas PB,et al. Mechanical properties of callus in human tibial fractures: a preliminary investigation[J]. Clin Biomech (Bristol,Avon),2001,16(9): 776-782.
(收稿日期:2009-11-06), http://www.100md.com(刘鸿麒 丁真奇)
随着骨科学的发展,尤其是骨折固定方法和固定原则的完善,不同干预因素对骨折愈合过程影响的各不相同,如何得到正确且精确的评价方法已越来越受到骨科界的注意,采用不同治疗方法时由于骨折愈合方式不同,也可能采用不同的测量方法。骨折愈合是多种因素相互协调、相互拮抗作用的结果。单一考虑某一因素而得出最终结论是不可靠的,并且,许多检测指标在临床上的推广有待进一步的研究和改进。一种指标不可能适合于所有骨折愈合过程的评价。
[参考文献]
[1] Whelan DB, Bhandari M, McKee MD, et al. Interobserver and intraobserver variation in the assessment of the healing of tibial fractures after intramedullary fixation[J]. J Bone Joint Surg Br,2002, 84:15-18.
, http://www.100md.com
[2] Szechinski JW,Grigorian MA,Grainger AJ,et al. Femoral neck and intertrochanteric fractures:radiographic indicators of fracture healing[J]. Orthopedics,2002,25:1365-1368.
[3] Cattermole HC,Fordham JN,Muckle DS,et al. Dual-energy X-ray absorptiometry as a measure of healing in fractures treated by intramedullary nailing[J]. J Orthop Trauma,1996,10:563-568.
[4] Smith MA,Jones EA,Strachan RK,et al. Prediction of fracture healing in the tibia by quantitative radionuclide imaging[J]. J Bone Joint Surg Br,1987,69:441-447.
, 百拇医药
[5] Wallace AL,Strachan RK,Blane A,et al. Quantitative early phase scintigraphy in the prediction of healing of tibial fractures[J]. Skeletal Radiol,1992,21:241-245.
[6] Bossy E,Talmant M,Peyrin F,et al. An in vitro study of the ultrasonic axial transmission technique at the radius: 1-MHz velocity measurements are sensitive to both mineralization and intracortical porosity[J]. J Bone Miner Res,2004,19(9):1548-1556.
[7] Lefebvre F,Deblock Y,Campistron P,et al. Development of a new ultrasonic technique for bone and biomaterials in vitro character- ization[J]. J Biomed Mater Res,2002,63(4):441-446.
, http://www.100md.com
[8] Malizos KN,Papachristos AA,Protopappas VC,et al. Transosseous application of low-intensity ultrasound for the enhancement and monitoring of fracture healing process in a sheep osteotomy model[J]. Bone,2006,38: 530-539.
[9] Protopappas VC,Baga DA,Fotiadis DI,et al. An ultrasound wearable system for the monitoring and acceleration of fracture healing in long bones[J]. IEEE Trans Biomed Eng,2005,52(9):1597-1608.
[10] Grigoryan M, Lynch JA, Fierlinger AL, et al. Quantitative and qualitative assessment of closed fracture healing using computed tomography and conventional radiography[J]. Acad Radiol,2003,10:1267-1273.
, 百拇医药
[11] Bhattacharyya T,Bouchard KA,Phadke A,et al. The accuracy of computed tomography for the diagnosis of tibial nonunion[J]. J Bone Joint Surg Am,2006,88:692-697.
[12] Den Boer FC,Bramer JA,Patka P,et al. Quantification of fracture healing with three-dimensional computed tomography[J]. Arch Orthop Trauma Surg,1998,117:345-350.
[13] Lowet G,Dayuan X,Van der Perre G. Study of the vibrational behaviour of ahealing tibia using finite element modelling[J]. J Biomech,1996,29:1003-1010.
, http://www.100md.com
[14] Glinkowski W,Górecki A. Clinical experiences with ultrasonometric measurement of fracture healing[J]. Technol Health Care,2006,14:321-333.
[15] Fellinger M,Leitgeb N,Szyszkowitz R,et al. Early detection of delayed union in lower leg fractures using a computerised analysis of mechanical vibration reactions of bone for assessing the state of fracture healing[J]. Arch Orthop Trauma Surg,1994,113:93-96.
[16] Moorcroft CI,Ogrodnik PJ,Thomas PB,et al. Mechanical properties of callus in human tibial fractures: a preliminary investigation[J]. Clin Biomech (Bristol,Avon),2001,16(9): 776-782.
(收稿日期:2009-11-06), http://www.100md.com(刘鸿麒 丁真奇)